Iberdomide (Cc220) Maintenance After Asct in Newly Diagnosed MM Patients

Status Active, not recruiting

Clinical Trial Summary

This is a phase II study to evaluate the efficacy and safety of different doses of iberdomide continuous therapy as maintenancetreatment after transplant.

Clinical Trial Description

This is a phase II study with two parallel cohorts of newly diagnosed multiple myeloma (NDMM) patients in at least partial response (PR) after induction with proteasome inhibitors (PIs) plus IMIDs and single or double ASCT Subjects will receive two dose levels of Iberdomide, they will be evaluated for efficacy and safety. In case, in one cohort will be registered unacceptable toxicity, a third cohort will be opened. Subjects will receive treatment until progression, intolerance or unacceptable toxicity. Subsequently subjects will be followed for 24 months. The maximum number of subjects is 130 for cohort 1 and 2, 160 in case a third cohort will be opened. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04564703
Study type	Interventional
Source	Stichting European Myeloma Network
Contact
Status	Active, not recruiting
Phase	Phase 2
Start date	February 22, 2021
Completion date	December 2027

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See also
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