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Clinical Trial Summary

By doing this study, researchers hope to learn the following:

- The safety of hyperbaric oxygen administration in the setting of the autologous transplant

- The effects of hyperbaric oxygen administration on neutrophil count recovery and engraftment


Clinical Trial Description

The post stem cell transplant complications of neutropenic fever and mucositis, related to the chemotherapy and/or radiation on hematopoietic tissue administered prior to peripheral blood stem cell transplant, are reversible upon neutrophil count recovery. The investigators will investigate the use of hyperbaric oxygen as an intervention to shorten neutropenia post-high-dose chemotherapy and autologous peripheral blood stem cell transplant. The idea of using hyperbaric oxygen therapy in autologous stem cell transplantation is based on the investigators pre-clinical work that supported the use of hyperbaric oxygen to improve umbilical cord blood (cluster of differentiation 34) CD34+ stem cell transplantation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02087657
Study type Interventional
Source University of Kansas Medical Center
Contact
Status Active, not recruiting
Phase N/A
Start date March 2014
Completion date August 2017

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