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Clinical Trial Summary

This protocol will investigate the effectiveness of plerixafor in the up-front setting in avoiding a second round of mobilization and whether this translates into a clinical and economic benefit.


Clinical Trial Description

Peripheral blood stem cells are now considered the standard source of stem cells for autologous stem cell transplants. Unfortunately, there is still a 20-30% chance that inadequate numbers of stem cells will be collected, resulting in prolonged recovery of cell counts after transplantation and increased transfusion dependence. There is also a significant economic burden associated with remobilization and a risk that delays in collecting sufficient numbers of stem cells can result in an increased chance of disease recurrence prior to transplantation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01339572
Study type Interventional
Source University of Florida
Contact
Status Completed
Phase Phase 2
Start date April 2011
Completion date November 2015

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