Connect® MM- The Multiple Myeloma Disease Registry

Multiple Myeloma Clinical Trial

Official title:

Connect® MM- The Multiple Myeloma Disease Registry

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT01081028
• Other study ID #: Connect ® MM
• Status: Active, not recruiting
• Start date: September 1, 2009
• Est. completion date: August 15, 2031

Study information

• Verified date: December 2023
• Source: Celgene
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of the Connect® MM Registry is to explore the natural history and real world management of patients with newly diagnosed symptomatic multiple myeloma (MM) and provide unique insights into the management of MM and the impact of this hematologic disorder on patients.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 3011
• Est. completion date: August 15, 2031
• Est. primary completion date: December 31, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Newly diagnosed with symptomatic MM within 2 months of enrollment in Connect®MM registry

• Age =18 years

• Willing and able to provide signed informed consent

• Agrees to complete patient assessment questionnaires either alone or with minimal assistance from caregivers and/or trained site personnel

Exclusion Criteria:

• None

Related Conditions & MeSH terms

• Multiple Myeloma
• Neoplasms, Plasma Cell

Locations

Country	Name	City	State
Puerto Rico	Auxilio Cancer Center	San Juan
United States	US Oncology - Texas Cancer Center - Abilene (South)	Abilene	Texas
United States	Summa Health System - Cancer Research Office	Akron	Ohio
United States	Phoebe Putney Memorial Hospital	Albany	Georgia
United States	US Oncology - Albany Medical Cancer Center	Albany	New York
United States	US Oncology - New York Oncology Hematology, PC-Albany	Albany	New York
United States	US Oncology - Texas Oncology, PA - Amarillo	Amarillo	Texas
United States	Central Utah Clinic	American Fork	Utah
United States	McFarland Clinic	Ames	Iowa
United States	US Oncology - Amsterdam Community Cancer Program	Amsterdam	New York
United States	Pacific Cancer Medical Center, Inc	Anaheim	California
United States	Fox Valley Hematology & Oncology	Appleton	Wisconsin
United States	US Oncology - Arlington Fairfax Hematology Oncology	Arlington	Virginia
United States	US Oncology - Texas Oncology - Arlington South	Arlington	Texas
United States	Cancer Care & Hematology Specialists of Chicagoland, PC	Arlington Heights	Illinois
United States	Georgia Cancer Specialists	Atlanta	Georgia
United States	Peachtree Hematology-Oncology Consultants	Atlanta	Georgia
United States	US Oncology- Rocky Mountain Cancer Center-Aurora	Aurora	Colorado
United States	Austin Cancer Centers	Austin	Texas
United States	US Oncology - South Austin Cancer Center	Austin	Texas
United States	US Oncology - Southwest Regional Cancer Center - North	Austin	Texas
United States	US Oncology - Texas Oncology - Midtown	Austin	Texas
United States	US Oncology - Texas Oncology Cancer Center	Austin	Texas
United States	US Oncology - Texas Oncology North Austin	Austin	Texas
United States	Mary Bird Perkins Cancer Center	Baton Rouge	Louisiana
United States	Michigan State University/Bay Regional Medical Center	Bay City	Michigan
United States	US Oncology - Texas Oncology, PA - Bedford	Bedford	Texas
United States	Indiana Blood and Marrow Transplant, LLC	Beech Grove	Indiana
United States	St. Francis Cancer Research	Beech Grove	Indiana
United States	Essex Oncology of North Jersey, PA	Belleville	New Jersey
United States	Peace Health Medical Group	Bellingham	Washington
United States	Alta Bates Summit Comprehensive Cancer Center	Berkeley	California
United States	Oncology Hematology of Lehigh Valley	Bethlehem	Pennsylvania
United States	Hematology Oncology Associates of the Quad Cities	Bettendorf	Iowa
United States	Legacy Pharma Research	Bismarck	North Dakota
United States	Med Center One	Bismarck	North Dakota
United States	US Oncology - Rocky Mountain Cancer Center-Boulder	Boulder	Colorado
United States	Collaborative Research Group	Boynton Beach	Florida
United States	Hematology Oncology Associates	Boynton Beach	Florida
United States	University Cancer Institute	Boynton Beach	Florida
United States	Bronx River Medical Associates	Bronx	New York
United States	Eastchester Center for Cancer Care	Bronx	New York
United States	St. Joseph Regional Cancer Center	Bryan	Texas
United States	Jonah Cancer Care Center & ECMC	Buffalo	New York
United States	Southbay Oncology Hematology Partners	Campbell	California
United States	Gabrail Cancer Center Research	Canton	Ohio
United States	US Oncology - Cancer Centers of North Carolina - Cary	Cary	North Carolina
United States	US Oncology - Texas Oncology Cedar Park	Cedar Park	Texas
United States	Iowa Blood and Cancer Care of PCI	Cedar Rapids	Iowa
United States	Charleston Hematology Oncology Associates, PA	Charleston	South Carolina
United States	The Center for Cancer and Hematologic Disease	Cherry Hill	New Jersey
United States	St. Louis Cancer Care, LLP	Chesterfield	Missouri
United States	John H. Stroger, Jr. Hospital of Cook County	Chicago	Illinois
United States	Rush University Medical Center	Chicago	Illinois
United States	Univeristy of Chicago Medical Center, Section of Hematology/Oncology	Chicago	Illinois
United States	Cleveland VA Medical Center	Cleveland	Ohio
United States	Scott & White Clinic	College Station	Texas
United States	Family Cancer Center, PLLC	Collierville	Tennessee
United States	US Oncology - Rocky Mountain Cancer Center-Colorado Springs	Colorado Springs	Colorado
United States	US Oncology- Rocky Mountain Cancer Center at the Pavillion	Colorado Springs	Colorado
United States	Mid Ohio Oncology/Hematology, Inc	Columbus	Ohio
United States	Flora Research Associates	Coral Springs	Florida
United States	Compassionate Cancer Care Medical Group (Corona)	Corona	California
United States	Coastal Bend Cancer Center	Corpus Christi	Texas
United States	South Texas Institute of Cancer	Corpus Christi	Texas
United States	Hematology & Oncology Associates of Rhode Island	Cranston	Rhode Island
United States	US Oncology - Texas Cancer Center at Medical City	Dallas	Texas
United States	US Oncology -Texas Oncology, PA - Dallas	Dallas	Texas
United States	Geisinger Medical Center	Danville	Pennsylvania
United States	Archbold Cancer Center	Deerfield Beach	Florida
United States	Flora Research Associates	Deerfield Beach	Florida
United States	US Oncology - Rocky Mountain Cancer Center-Midtown	Denver	Colorado
United States	US Oncology - Rocky Mountain Cancer Center-Rose	Denver	Colorado
United States	Consultants in Medical Oncology and Hematology, PC	Drexel Hill	Pennsylvania
United States	Duluth Clinic Cancer Center	Duluth	Minnesota
United States	DUMC Division of Cellular Therapy/ABMT	Durham	North Carolina
United States	US Oncology - Cancer Centers of the Carolinas - Easley	Easley	South Carolina
United States	US Oncology - Puget Sound Cancer Center-Edmonds	Edmonds	Washington
United States	US Oncology - El Paso Cancer Treatment Ctr	El Paso	Texas
United States	Elmhurst Memorial Hospital	Elmhurst	Illinois
United States	Hematology Oncology Center, Inc	Elyria	Ohio
United States	Drs. Forte, Schleider, Attas & Condemi, PA	Englewood	New Jersey
United States	Southwest Cancer Care	Escondido	California
United States	US Oncology - Willamette Valley Cancer Institute - Eugene	Eugene	Oregon
United States	Northshore University Health System	Evanston	Illinois
United States	Providence Everett Medical Center	Everett	Washington
United States	US Oncology - Fairfax-Northern VA Hem-Onc PC	Fairfax	Virginia
United States	Medical Specialists of Fairfield	Fairfield	Connecticut
United States	Roger Maris Cancer Center	Fargo	North Dakota
United States	Genesys Hurley Cancer Institute	Flint	Michigan
United States	Michigan State University/McLaren Regional Medical Center	Flint	Michigan
United States	Broward Oncology Associates, PA	Fort Lauderdale	Florida
United States	St. Edward Mercy Medical Center	Fort Smith	Arkansas
United States	US Oncology - Southwest Forth Worth Cancer Center	Fort Worth	Texas
United States	US Oncology - Texas Oncology, PA - Forth Worth	Fort Worth	Texas
United States	Compassionate Cancer Care Medical Group (Fountain Valley)	Fountain Valley	California
United States	Virginia K. Crosson Cancer Center	Fullerton	California
United States	Florida Cancer Specialists & Research Institute	Gainesville	Florida
United States	US Oncology - Fairfax Northern Virginia Hematology-Oncology, PC-Gainesville	Gainesville	Virginia
United States	US Oncology - Texas Oncology, PA - Garland	Garland	Texas
United States	Center for Cancer Care @ Goshen Health Systems	Goshen	Indiana
United States	TORI - St. Mary's Advanced Medical Pavilion	Grand Junction	Colorado
United States	US Oncology - Texas Oncology - Grapevine	Grapevine	Texas
United States	St. Vincent Hospital/Green Bay Oncology	Green Bay	Wisconsin
United States	US Oncology - Cancer Centers of the Carolinas - Butternut	Greenville	South Carolina
United States	US Oncology - Cancer Centers of the Carolinas - Eastside	Greenville	South Carolina
United States	US Oncology - Cancer Centers of the Carolinas - West Faris	Greenville	South Carolina
United States	Andrews and Patel Associates	Harrisburg	Pennsylvania
United States	Ingalls Cancer Research Center	Harvey	Illinois
United States	TORI - Comprehensive Cancer Centers of NV	Henderson	Nevada
United States	Carolina Oncology Specialists, PA	Hickory	North Carolina
United States	Emerywood Hematology/Oncology	High Point	North Carolina
United States	SC Cancer Specialists, PA	Hilton Head Island	South Carolina
United States	Memorial Cancer Institute	Hollywood	Florida
United States	Straub Clinic and Hospital	Honolulu	Hawaii
United States	Genesis Cancer Center	Hot Springs	Arkansas
United States	MD Anderson Cancer Center	Houston	Texas
United States	The Methodist Hospital Research Institute-AOCT	Houston	Texas
United States	US Oncology - Cavell Cancer Treatment Program	Hudson	New York
United States	US Oncology - Florida Cancer Institute - New Hope-Hudson	Hudson	Florida
United States	The Cancer Center of Huntsville	Huntsville	Alabama
United States	Capecod Hospital/Davenport Mugar Cancer Center	Hyannis	Massachusetts
United States	Indiana University Cancer Center Clinical Research Office	Indianapolis	Indiana
United States	Southlake Oncology dba Las Colinas Hematology Oncology	Irving	Texas
United States	Jackson Oncology Associates	Jackson	Mississippi
United States	Integrated Community Oncology Network, LLC	Jacksonville	Florida
United States	Capitol Comprehensive Cancer Care Clinic	Jefferson City	Missouri
United States	Broome Oncology	Johnson City	New York
United States	Joliet Oncology	Joliet	Illinois
United States	Clopton Clinic Hematology/Oncology	Jonesboro	Arkansas
United States	West Michigan Cancer Center	Kalamazoo	Michigan
United States	Columbia Basin Hematology and Oncology	Kennewick	Washington
United States	US Oncology - San Antonio Tumor & Blood Clinic - Kerrville	Kerrville	Texas
United States	US Oncology - Medical Oncology Associates (Nahar)	Kingston	Pennsylvania
United States	US Oncology - Texas Oncology - Kyle	Kyle	Texas
United States	Arena Oncology Associates, PC	Lake Success	New York
United States	Watson Clinic	Lakeland	Florida
United States	US Oncology - Rocky Mountain Cancer Center-Lakewood	Lakewood	Colorado
United States	Lancaster Cancer Center	Lancaster	Pennsylvania
United States	TORI - Antelope Valley Cancer Center	Lancaster	California
United States	Michigan State University/Breslin Cancer Center	Lansing	Michigan
United States	Michigan State University/Lapeer Regional Medical Center	Lapeer	Michigan
United States	Southern Nevada Cancer Research Foundation	Las Vegas	Nevada
United States	US Oncology - New York Oncology Hematology, PC-Latham	Latham	New York
United States	Cancer & Blood Disease Center	Lecanto	Florida
United States	US Oncology - Fairfax-Northern Virgina Hem-Onc, PC-Leesburg	Leesburg	Virginia
United States	Nebraska Hematology Oncology, PC	Lincoln	Nebraska
United States	Southeast Nebraska Hematology & Oncology Consultants, PC	Lincoln	Nebraska
United States	Little Rock Hematology Oncology Associates, PA	Little Rock	Arkansas
United States	US Oncology - Rocky Mountain Cancer Center-Littleton	Littleton	Colorado
United States	US Oncology - Rocky Mountain Cancer Center-Sky Ridge	Lone Tree	Colorado
United States	US Oncology - Rocky Mountain Cancer Center-Longmont	Longmont	Colorado
United States	US Oncology - Longview Cancer Center	Longview	Texas
United States	Baptist Hospital East	Louisville	Kentucky
United States	Joe Arrington Cancer Research and Treatment Center	Lubbock	Texas
United States	Medical Oncology and Blood Disorders, LLP	Manchester	Connecticut
United States	US Oncology - Allison Cancer Center	Midland	Texas
United States	CMS Water Tower Medical Commons Medical Oncology #100	Milwaukee	Wisconsin
United States	Montana Cancer Institute Foundation	Missoula	Montana
United States	Medical Arts Associates, Ltd	Moline	Illinois
United States	Monterey Bay Oncology	Monterey	California
United States	West Virginia University - Clinical Trials Research Unit	Morgantown	West Virginia
United States	Hematology-Oncology Associates of Northern NJ dba Carol G. Simon	Morristown	New Jersey
United States	Michigan State University/Mount Clemens Regional Medical Center	Mount Clemens	Michigan
United States	Cancer Research-Munster	Munster	Indiana
United States	SCRI	Nashville	Tennessee
United States	Cancer Care Center Inc.	New Albany	Indiana
United States	Hospital of Central Connecticut	New Britain	Connecticut
United States	Pasco Hernando Oncology Associates (Kumar)	New Port Richey	Florida
United States	US Oncology - Florida Cancer Institute - New Hope-New Port Richey	New Port Richey	Florida
United States	Delaware Clinical & Laboratory Physicians, PA	Newark	Delaware
United States	Oncology Hematology Associates of SW IN	Newburgh	Indiana
United States	Oncology Specialists, S.C.	Niles	Illinois
United States	TORI - North Valley Hematology/Oncology	Northridge	California
United States	Newland Medical Associates	Novi	Michigan
United States	Hematology Oncology Associates	Oakland	California
United States	US Oncology - Texas Oncology - Odessa	Odessa	Texas
United States	Northern Utah Associates	Ogden	Utah
United States	Michigan State University/Memorial Cancer Center	Owosso	Michigan
United States	Comprehensive Cancer Center	Palm Springs	California
United States	US Oncology - Rocky Mountain Cancer Center-Parker	Parker	Colorado
United States	Sacred Heart Medical Oncology Group	Pensacola	Florida
United States	Illinois Cancer Care	Peoria	Illinois
United States	The Western Pennsylvania Hospital	Pittsburgh	Pennsylvania
United States	UPCI Hillman Cancer Center	Pittsburgh	Pennsylvania
United States	US Oncology - North Texas Regional Cancer Center	Plano	Texas
United States	US Oncology - Texas Oncology Plano West Cancer Center	Plano	Texas
United States	Bay Area Cancer Research Group, LLC	Pleasant Hill	California
United States	New Hope Cancer & Research Institute	Pomona	California
United States	US Oncology - Cancer Centers of North Carolina - Falls	Raleigh	North Carolina
United States	Berks Hematology Oncology Associates	Reading	Pennsylvania
United States	VA Sierra Nevada Healthcare System	Reno	Nevada
United States	US Oncology - New York Oncology Hematology, PC-Rexford	Rexford	New York
United States	Campassionate Cancer Care Medical Group (Riverside)	Riverside	California
United States	Cancer Care Centers of Brevard	Rockledge	Florida
United States	Capitol Hematology Oncology Medical Group - Sutter Roseville	Roseville	California
United States	US Oncology - Texas Oncology - Round Rock Cancer Center	Round Rock	Texas
United States	US Oncology - Texas Oncology Seton Williamson	Round Rock	Texas
United States	St. Joseph Oncology	Saint Joseph	Missouri
United States	Hematology Oncology Consultants, Inc	Saint Louis	Missouri
United States	St. John's Mercy Medical Center	Saint Louis	Missouri
United States	University Hematology Oncology, Inc.	Saint Louis	Missouri
United States	Washington University in St. Louis, Division of Oncology, Section of Bone Marrow Transplantation & Leukemia	Saint Louis	Missouri
United States	Park Nicollet Institute - Louisiana Ave.	Saint Louis Park	Minnesota
United States	University of Utah - Huntsman Cancer Institute	Salt Lake City	Utah
United States	US Oncology - Cancer Care Centers of South Texas	San Antonio	Texas
United States	US Oncology - HOAST - Medical Dr.	San Antonio	Texas
United States	US Oncology - San Antonio Tumor & Blood Clinic - M. Oak	San Antonio	Texas
United States	US Oncology - Texas Oncology - San Marcos	San Marcos	Texas
United States	TORI - Central Coast Medical Oncology	Santa Maria	California
United States	Redwood Regional Medical Group, Inc.	Santa Rosa	California
United States	Summit Cancer Care	Savannah	Georgia
United States	US Oncology - Puget Sound Cancer Center-Seattle	Seattle	Washington
United States	US Oncology - Cancer Center of the Carolinas - Seneca	Seneca	South Carolina
United States	Siouxland Hematology-Oncology Associates, LLP	Sioux City	Iowa
United States	Avera Cancer Institute	Sioux Falls	South Dakota
United States	Sanford Clinic	Sioux Falls	South Dakota
United States	Orchard Research	Skokie	Illinois
United States	Steeplechase Cancer Center	Somerville	New Jersey
United States	Northern Indiana Cancer Research Consortium	South Bend	Indiana
United States	Newland Medical Associates	Southfield	Michigan
United States	US Oncology - Cancer Centers of the Carolinas - Spartanburg	Spartanburg	South Carolina
United States	Medical Oncology Associates PS	Spokane	Washington
United States	US Oncology - Cancer Care Northwest - Sherman	Spokane	Washington
United States	St. John's Medical Research Institute	Springfield	Missouri
United States	US Oncology - Willamette Valley Cancer Institute - Springfield	Springfield	Oregon
United States	Hematology Oncology, PC	Stamford	Connecticut
United States	Stockton Hematology Oncology Medical Group, Inc.	Stockton	California
United States	SUNY Upstate Medical University - Adult Program	Syracuse	New York
United States	Scott & White Healthcare Department of Research	Temple	Texas
United States	Florida Hospital Waterman-Lake County Oncology & Hematology	The Villages	Florida
United States	US Oncology - Rocky Mountain Cancer Center-Thornton	Thornton	Colorado
United States	US Oncology - Troy Cancer Treatment Program	Troy	New York
United States	US Oncology - Arizona Oncology Associates - Rudasill	Tucson	Arizona
United States	DCH Health System	Tuscaloosa	Alabama
United States	ETMC dba Blood and Cancer Center - East Texas	Tyler	Texas
United States	ETMC dba Tyler Hematology Oncology	Tyler	Texas
United States	Carle Cancer Center	Urbana	Illinois
United States	US Oncology - Texas Oncology Cancer Care and Research Center	Waco	Texas
United States	Providence St. Mary Regional Cancer Center	Walla Walla	Washington
United States	Cedar Valley Medical Specialists	Waterloo	Iowa
United States	Covenant Clinic	Waterloo	Iowa
United States	Waukesha Memorial Hospital	Waukesha	Wisconsin
United States	Institute for Myeloma and Bone Cancer Research	West Hollywood	California
United States	Alliance Hematology Oncology, PA	Westminster	Maryland
United States	Cleveland Clinic Florida	Weston	Florida
United States	Cancer Center of Kansas, PA	Wichita	Kansas
United States	US Oncology - Texoma Cancer Center	Wichita Falls	Texas
United States	US Oncology - Shenandoah Oncology - Winchester	Winchester	Virginia
United States	US Oncology - Fairfax-Northern Virginia Hem-Onc, PC-Woodbridge	Woodbridge	Virginia
United States	Lawrence M. Stallings MD LTD dba Trilogy Cancer Care	Wooster	Ohio
United States	Fallon Clinic	Worcester	Massachusetts
United States	US Oncology - Yakima Valley Memorial Hospital/North Star Lodge	Yakima	Washington

Sponsors (1)

Lead Sponsor	Collaborator
Celgene

Countries where clinical trial is conducted

United States,  Puerto Rico, 

References & Publications (12)

Abonour R, Rifkin RM, Gasparetto C, Toomey K, Durie BGM, Hardin JW, Terebelo HR, Jagannath S, Narang M, Ailawadhi S, Omel JL, Lee HC, Srinivasan S, Kitali A, Agarwal A, Wagner L; CONNECT MM Registry Investigators. Effect of initial treatment on health-rel — View Citation

Abonour R, Wagner L, Durie BGM, Jagannath S, Narang M, Terebelo HR, Gasparetto CJ, Toomey K, Hardin JW, Kitali A, Gibson CJ, Srinivasan S, Swern AS, Rifkin RM. Impact of post-transplantation maintenance therapy on health-related quality of life in patient — View Citation

Ailawadhi S, Jagannath S, Lee HC, Narang M, Rifkin RM, Terebelo HR, Durie BGM, Toomey K, Hardin JW, Gasparetto CJ, Wagner L, Omel JL, He M, Yue L, Flick ED, Agarwal A, Abonour R; Connect MM Registry Investigators. Association between race and treatment pa — View Citation

Jagannath S, Abonour R, Durie BGM, Gasparetto C, Hardin JW, Narang M, Terebelo HR, Toomey K, Wagner L, Srinivasan S, Kitali A, Yue L, Flick ED, Agarwal A, Rifkin RM. Heterogeneity of Second-Line Treatment for Patients With Multiple Myeloma in the Connect — View Citation

Jagannath S, Abonour R, Durie BGM, Narang M, Terebelo HR, Gasparetto CJ, Toomey K, Hardin JW, Wagner L, Agarwal A, Srinivasan S, Kitali A, Flick ED, Sturniolo M, Rifkin RM. Impact of post-ASCT maintenance therapy on outcomes in patients with newly diagnos — View Citation

Jagannath S, Rifkin RM, Gasparetto CJ, Toomey K, Durie BGM, Hardin JW, Terebelo HR, Wagner L, Narang M, Ailawadhi S, Omel JL, Srinivasan S, He M, Ung B, Kitali A, Flick ED, Agarwal A, Abonour R; CONNECT MM Registry Investigators. Treatment Journeys of Pat — View Citation

Rifkin RM, Abonour R, Shah JJ, Mehta J, Narang M, Terebelo H, Gasparetto C, Toomey K, Hardin JW, Lu JJ, Kenvin L, Srinivasan S, Knight R, Nagarwala Y, Durie BG. Connect MM(R) - the Multiple Myeloma Disease Registry: incidence of second primary malignancie — View Citation

Rifkin RM, Abonour R, Terebelo H, Shah JJ, Gasparetto C, Hardin J, Srinivasan S, Ricafort R, Nagarwala Y, Durie BG. Connect MM Registry: The Importance of Establishing Baseline Disease Characteristics. Clin Lymphoma Myeloma Leuk. 2015 Jun;15(6):368-76. do — View Citation

Rifkin RM, Jagannath S, Durie BGM, Narang M, Terebelo HR, Gasparetto CJ, Toomey K, Hardin JW, Wagner L, Parikh K, Abouzaid S, Srinivasan S, Kitali A, Zafar F, Abonour R. Treatment Outcomes and Health Care Resource Utilization in Patients With Newly Diagnosed Multiple Myeloma Receiving Lenalidomide-only Maintenance, Any Maintenance, or No Maintenance: Results from the Connect MM Registry. Clin Ther. 2018 Jul;40(7):1193-1202.e1. doi: 10.1016/j.clinthera.2018.05.017. Epub 2018 Jul 23. — View Citation

Shah JJ, Abonour R, Gasparetto C, Hardin JW, Toomey K, Narang M, Srinivasan S, Kitali A, Zafar F, Flick ED, Rifkin RM. Analysis of Common Eligibility Criteria of Randomized Controlled Trials in Newly Diagnosed Multiple Myeloma Patients and Extrapolating Outcomes. Clin Lymphoma Myeloma Leuk. 2017 Sep;17(9):575-583.e2. doi: 10.1016/j.clml.2017.06.013. Epub 2017 Jun 17. — View Citation

Terebelo H, Srinivasan S, Narang M, Abonour R, Gasparetto C, Toomey K, Hardin JW, Larkins G, Kitali A, Rifkin RM, Shah JJ. Recognition of early mortality in multiple myeloma by a prediction matrix. Am J Hematol. 2017 Sep;92(9):915-923. doi: 10.1002/ajh.24 — View Citation

Terebelo HR, Abonour R, Gasparetto CJ, Toomey K, Durie BGM, Hardin JW, Jagannath S, Wagner L, Narang M, Flick ED, Srinivasan S, Yue L, Kitali A, Agarwal A, Rifkin RM; CONNECT MM Registry Investigators. Development of a prognostic model for overall survival in multiple myeloma using the Connect(R) MM Patient Registry. Br J Haematol. 2019 Dec;187(5):602-614. doi: 10.1111/bjh.16139. Epub 2019 Aug 5. — View Citation

* Note: There are 12 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Identify and summarize patterns in therapeutic regimens	Describe practice patterns of common first-line treatment regimens and subsequent therapeutic strategies in patients newly diagnosed with symptomatic MM in the community and academic setting	Minimum 8 years
Primary	Identify and summarize patterns in therapeutic regimens and patient outcomes	Provide insight into treatment regimens and therapy sequence in clinical practice as they relate to clinical outcomes (response, overall survival, progression-free survival) in patients newly diagnosed with symptomatic MM	Minimum 8 years
Secondary	Summarize Effectiveness of Treatment Regimens	Describe any differences in effectiveness associated with different treatment regimens, including common first-line regimens, subsequent therapeutic strategies and regional effects (such as proximity of academic centers) in patients newly diagnosed with symptomatic MM	Minimum 8 years
Secondary	Summarize health-related quality of life (HRQoL) relation to treatment regimens/sequence and clinical outcomes	Describe the health-related quality of life (HRQoL) of patients newly diagnosed with symptomatic MM, and to explore the association with HRQoL of treatment regimens/sequence and clinical outcomes	Minimum 8 years