Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors (Cohorts A, B and C)

MSI Negative Colorectal Cancer Clinical Trial

Official title: Phase 2 Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors

Status Completed

Clinical Trial Summary

This study will be looking at whether MK-3475 (an antibody that blocks negative signals to T cells) is effective (anti-tumor activity) and safe in three different patient populations. These include: 1. patients with MSI positive colon cancer, 2. patients with MSI negative colon cancer and 3. patients with other MSI positive cancers.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Colorectal Neoplasms
• Microsatellite Instability
• MSI Negative Colorectal Cancer
• MSI Positive Colorectal Cancer
• MSI Positive Non-Colorectal Cancers

• NCT number: NCT01876511
• Study type: Interventional
• Source: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
• Status: Completed
• Phase: Phase 2
• Start date: September 2013
• Completion date: August 2019