Clinical Trials Logo

Clinical Trial Summary

This is a Phase 3, multi-center, randomized withdrawal study to evaluate the efficacy and durability of ampreloxetine in participants with MSA and symptomatic nOH after 20 weeks of treatment. This study includes 4 periods: Screening, open label, randomized withdrawal, and long-term treatment extension (LTE).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05696717
Study type Interventional
Source Theravance Biopharma
Contact Theravance Biopharma
Phone 1-855-633-8479
Email medinfo@theravance.com
Status Recruiting
Phase Phase 3
Start date June 27, 2023
Completion date January 2027

See also
  Status Clinical Trial Phase
Recruiting NCT02194816 - Modifiable Variables in Parkinsonism (MVP)
Recruiting NCT05698017 - Study to Evaluate Investigational Allogeneic Cell Therapy Product hOMSC300 for Treatment of Early- to Moderate Stage MSA Phase 1/Phase 2
Enrolling by invitation NCT04680130 - Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders
Recruiting NCT05486806 - Longitudinal Tracking of Patients Diagnosed With Neurodegenerative Movement Disorders
Completed NCT03577483 - Differential Diagnosis Between Parkinson's Disease and Multiple System Atrophy Using Digital Speech Analysis N/A
Recruiting NCT02795052 - Neurologic Stem Cell Treatment Study N/A
Recruiting NCT05197816 - MotIoN aDaptive Deep Brain Stimulation for MSA N/A
Not yet recruiting NCT06120049 - [18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DBL vs. AD Phase 2/Phase 3
Completed NCT05011773 - Manipulating and Optimising Brain Rhythms for Enhancement of Sleep N/A
Recruiting NCT05792332 - Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study) N/A