Mortality Clinical Trial
Official title:
Periinterventional Outcome Study in the Elderly (POSE): European, Multi-centre, Prospective Observational Cohort Study
The POSE study will predict critical stages and outcome in a large sample of all surgical and non-surgical interventional patients ≥80 years of age in Europe.
Elderly population (≥80 years) will increase from 5.3% of the total population in 2015 to 9%
in 2040. This implies an increasing number and variety of surgical and non-surgical
interventional procedures. Little is known about the in-hospital mortality rates in the
overall elderly interventional population. Compared with younger interventional patients, the
elderly are at greater risk of peri-interventional mortality and morbidity, because of
decline in physiological and cognitive reserve, and frequent comorbidities. Previous data are
mostly limited to specific populations, like the elderly hip fracture patient.
The investigators aim to recruit as many as possible centers throughout Europe, to
participate in this study. A total sample size of 7500 patients will provide reasonable and
valid results for the study aims. The primary endpoint will be analysed by fitting a
COX-Regression model to the data of the post-interventional mortality until day 30.
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