Morbidity Clinical Trial
Official title:
Biofilms on Short-term Indwelling Ureteral Stents: Influence on Associated Symptoms and Complications; Prediction by Urine Analysis; Current Bacterial Spectrum and Antibiotic Resistance
This study is performed to analyze various aspects of biofilms on ureteral stents.
The study is performed to provide a better understanding of the influence of biofilms on
ureteral stents on the entire spectrum of stent-associated morbidity.
Moreover, it could provide more detailed knowledge about the correlation of the occurrence of
biofilms on ureteral stents and findings in urinary analysis, which could serve as a decision
support whether patients with ureteral stents undergoing further interventions (for example
ESWL or simple secondary URS) should receive antibiotic prophylaxis.
Correlation of results of urinary bacteriologies (assessed pre- and intraoperatively) and
biofilm analysis on stents could provide information if "targeted antibiotic treatment" based
on urinary bacteriology only is possible at all.
Correlation of urinary analysis and conventional urinary bacteriology could provide a
valuable contribution regarding the prediction of bacteriuria and the necessity of postponing
operations.
Additionally, the study is intended to provide an overview over the recent bacterial species
that are involved into biofilms on ureteral stents and their resistance to antibiotics. This
could provide valuable information about the choice of antibiotics in cases were treatment
has to be performed empirically.
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