The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men

Mood Clinical Trial

— WEXMO  

Official title:

The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05033665
• Other study ID #: STUDY00013646
• Status: Completed
• Phase: N/A
• Start date: May 26, 2021
• Est. completion date: April 26, 2023

Study information

• Verified date: August 2023
• Source: Arizona State University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Dehydration is defined as the state of water deficit due to excessive water losses and/or small water intake. Underhydration is the result of inadequate water intake leading to activation of water hormonal homeostasis, characterized by elevated vasopressin, lower urinary output, and concentrated urine without any measurable changes in total body water. It is well established that dehydration (water deficit) decreases exercise performance and worsens mood, mainly in women. However, the impact of increased water intake in underhydrated individuals on their exercise capacity and mood is not known.

The aim of the proposed study is to investigate the impact of increased water intake in underhydrated individuals on aerobic exercise performance and mood in both women and men.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 217
• Est. completion date: April 26, 2023
• Est. primary completion date: April 26, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Healthy adults

• Residence in Arizona

Exclusion Criteria:

• Use of diuretics

• Use of anti-depressive medication

• Current pregnancy or lactation

• Current use of injectable insulin

• Diagnosed with irritable bowel syndrome

• Do not pass the Physical Activity Readiness Questionnaire for Everyone (PAR-Q) screening

Related Conditions & MeSH terms

• Dehydration
• Mood

Intervention

Behavioral:
• Increase water consumption
The underhydrated individuals will be instructed to increase their water intake for one week in order to meet the following two criteria: a) urinate at least 7 times per day and b) have straw-like color urine. A 2-mile run will be completed before and after the 7-day intervention.
• Maintain adequate water consumption
The subjects that are classified as euhydrated will be asked to maintain high water intake for one week to ensure proper hydration. A 2-mile run will be completed before and after the 7-day intervention.

Locations

Country	Name	City	State
United States	Interdisciplinary Science and Technology Building 8	Phoenix	Arizona

Sponsors (1)

Lead Sponsor	Collaborator
Arizona State University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	2-mile run-time (min)		Day 1
Primary	2-mile run-time (min)		Day 8
Primary	Mood	Profile of Mood States questionnaire (POMS 2®-Adult Short, Multi-Health Systems Inc.)	Pre-trial on day 1
Primary	Mood	Profile of Mood States questionnaire (POMS 2®-Adult Short, Multi-Health Systems Inc.)	Post-trial on day 1
Primary	Mood	Profile of Mood States questionnaire (POMS 2®-Adult Short, Multi-Health Systems Inc.)	Pre-trial on day 8
Primary	Mood	Profile of Mood States questionnaire (POMS 2®-Adult Short, Multi-Health Systems Inc.)	Post-trial on day 8
Primary	Urine osmolality (mmol/kg)		4 - 8 PM on day 0
Primary	Urine osmolality (mmol/kg)		4 - 8 PM on day 7
Primary	Urine osmolality (mmol/kg)		Upon waking (first morning sample) on day 1
Primary	Urine osmolality (mmol/kg)		Upon waking (first morning sample) on day 8
Primary	Urine specific gravity		4 - 8 PM on day 0
Primary	Urine specific gravity		4 - 8 PM on day 7
Primary	Urine specific gravity		Upon waking (first morning sample) on day 1
Primary	Urine specific gravity		Upon waking (first morning sample) on day 8
Secondary	Urine color	Armstrong validated 8-color scale. Minimum score: 1. Maximum score: 8. A higher score indicates a worse outcome (e.g., dehydrated).	4 - 8 PM on day 0
Secondary	Urine color	Armstrong validated 8-color scale. Minimum score: 1. Maximum score: 8. A higher score indicates a worse outcome (e.g., dehydrated).	4 - 8 PM on day 7
Secondary	Urine color	Armstrong validated 8-color scale. Minimum score: 1. Maximum score: 8. A higher score indicates a worse outcome (e.g., dehydrated).	Upon waking (first morning sample) on day 1
Secondary	Urine color	Armstrong validated 8-color scale. Minimum score: 1. Maximum score: 8. A higher score indicates a worse outcome (e.g., dehydrated).	Upon waking (first morning sample) on day 8
Secondary	Thirst perception	175 mm visual analog scale. Minimum score: 0 (not thirsty at all). Maximum score: 175 (extremely thirsty). A higher score indicates a worse outcome (e.g., more thirsty).	4 - 8 PM on day 0
Secondary	Thirst perception	175 mm visual analog scale. Minimum score: 0 (not thirsty at all). Maximum score: 175 (extremely thirsty). A higher score indicates a worse outcome (e.g., more thirsty).	4 - 8 PM on day 7
Secondary	Thirst perception	175 mm visual analog scale. Minimum score: 0 (not thirsty at all). Maximum score: 175 (extremely thirsty). A higher score indicates a worse outcome (e.g., more thirsty).	Upon waking (first morning sample) on day 1
Secondary	Thirst perception	175 mm visual analog scale. Minimum score: 0 (not thirsty at all). Maximum score: 175 (extremely thirsty). A higher score indicates a worse outcome (e.g., more thirsty).	Upon waking (first morning sample) on day 8