Validation of the Chinese Version of Oxford Depression Questionnaire

Mood Disorders Clinical Trial

Official title:

Psychometric Properties of the Oxford Depression Questionnaire in Chinese Patients With Mood Disorders

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05535270
• Other study ID #: IIT20220240B-R1
• Status: Completed
• Start date: January 1, 2022
• Est. completion date: June 30, 2023

Study information

• Verified date: September 2023
• Source: First Affiliated Hospital of Zhejiang University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Mood disorders are a group of psychiatric disorders that can affect a person's mood, energy, and motivation. Emotional blunting has been observed in clinical practice in patients with mood disorders. Emotional blunting has a negative impact on patients' overall treatment and leads to poorer adherence. The Oxford Depression Questionnaire (ODQ) is a measuring instrument of emotional blunting. The ODQ is expected to be a scientifically valid tool for detecting emotional blunting. The ODQ has high construct validity and internal reliability. However, no scientific validity studies have been conducted on ODQ in Chinese population. Therefore, this study is intended to investigate the reliability and validity of the ODQ in Chinese patients with mood disorders.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 272
• Est. completion date: June 30, 2023
• Est. primary completion date: June 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 13 Years to 65 Years

Eligibility

Inclusion Criteria:

1) both biological parents were Han Chinese; 2) currently diagnosed with major depressive disorder or bipolar disorder according to the Mini International Neuropsychiatric Interview for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition; 3) aged 13-65 years; 4) can complete the self-assessment questionnaires.

Exclusion Criteria:

1) currently diagnosed with neurological diseases or other major psychiatric disorders, e.g., schizophrenia, cognitive impairment, substance abuse; 2) diagnosed with severe somatic illnesses, such as diabetes and cardiovascular diseases;

Related Conditions & MeSH terms

• Mood Disorders

Intervention

Diagnostic Test:
• Oxford Depression Questionnaire (ODQ)
The Oxford Depression Questionnaire (ODQ)is a patient-centered questionnaire. The scale contains three sections: i) the patient's experience in the past week; ii) the patient's experience before the illness worsened, and iii) the patient's emotional feelings about receiving antidepressant treatment. The 26-item questionnaire contains four dimensions of "emotional blunting": not caring (NC), emotional detachment from others (ED), reduction in positive emotions (RP), and general reduction in emotions (GR). Patients not taking antidepressants were only required to rate the first two sections .

Locations

Country	Name	City	State
China	Department of Psychiatry, First Affiliated Hospital of Zhejiang University	Hangzhou	Zhejiang

Sponsors (1)

Lead Sponsor	Collaborator
First Affiliated Hospital of Zhejiang University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Oxford Depression Questionnaire (ODQ)	To analyze reliability and validity of the ODQ.	baseline
Secondary	Beck Depression Inventory-II (BDI-II)	To analyze criterion validity of the Chinese version of the ODQ	baseline
Secondary	Montgomery-Asberg Depression Rating Scale (MADRS)	To analyze correlation with ODQ	baseline
Secondary	Oxford Depression Questionnaire (ODQ)	To analyze Test-retest reliability coefficients of the ODQ.	2 weeks after baseline