Monkeypox Clinical Trial
— POXSPERMOfficial title:
Pilot Study to Detect Monkey Pox Virus in Sperm: POXSPERM
Given the current emerging epidemic of the MonkeyPox Virus (MPXV) and its route of transmission, the main objective of this pilot study is to characterize the presence of the MPXV in the semen of patients in the acute phase of infection and following this infection.
Status | Not yet recruiting |
Enrollment | 30 |
Est. completion date | November 2024 |
Est. primary completion date | November 2024 |
Accepts healthy volunteers | No |
Gender | Male |
Age group | 18 Years to 50 Years |
Eligibility | Inclusion Criteria: - in the acute phase of MPXV infection and whose PCR reveals the viral genome in a skin sample or in any other sample. - able to travel to the laboratory for the samples - who gave his free and informed consent and having signed the consent - Patient affiliated to a social security scheme or equivalent Exclusion Criteria: - Patient who has previously consulted for male infertility or who has previously performed an abnormal semen test (WHO standard) - Patient with ejaculation disorder or unable to collect semen or with abnormal semen volume (<1.5 mL). - Patient who presents serious clinical signs that do not allow him to travel to the investigation center. - Patient under a protection regime (including guardianship, curatorship or safeguard of justice) |
Country | Name | City | State |
---|---|---|---|
France | CHU Toulouse | Toulouse |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Toulouse |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | MPXV genomic DNA | presence of MPXV DNA in the semen and others body fluids of infected patients in the acute phase and during the follow-up. | Day 0 |
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT05512949 -
Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Monkeypox Vaccine
|
Phase 2 | |
Completed |
NCT05976100 -
Study of the Safety, Tolerability, Pharmacokinetics of NIOCH-14 in Volunteers Aged 18-50 Years
|
Phase 1 | |
Recruiting |
NCT05988203 -
A Clinical Study Investigating the Safety and Immune Responses After Immunization With Investigational Monkeypox Vaccines
|
Phase 1 | |
Terminated |
NCT05567939 -
Clinical, Virological, Immunological, Psychosocial and Epidemiological Consequences of Human Monkeypox Virus (ProMPX)
|
||
Active, not recruiting |
NCT05562323 -
Characterization of Vaccine-induced Responses Against Monkeypox (MoVIHvax) An Observational Prospective Cohort Study
|
||
Recruiting |
NCT05534984 -
Study of Tecovirimat for Human Monkeypox Virus
|
Phase 3 | |
Not yet recruiting |
NCT05745987 -
Smallpox Vaccine for Mpox Post-Exposure Prophylaxis: A Cluster RCT
|
Phase 4 | |
Not yet recruiting |
NCT05784038 -
Observational, Prospective, Cohort Study of Mpox Infection in Brazil (NETPOX)
|
||
Recruiting |
NCT05879965 -
Prospective Study for the FOLLOW-UP of Human Monkeypox Cases and Smallpox Vaccinees at Risk
|
||
Completed |
NCT03745131 -
Cohort Study of Healthcare Workers Receiving Imvanex®
|
||
Recruiting |
NCT05559099 -
Tecovirimat for Treatment of Monkeypox Virus
|
Phase 2 | |
Completed |
NCT05846243 -
Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years
|
Phase 2/Phase 3 | |
Recruiting |
NCT05654883 -
New York City Observational Study of Mpox Immunity
|
||
Completed |
NCT05762523 -
Safety and Tolerability Study of the VAC∆6 Vaccine in Volunteers Aged 18-40 Years
|
Phase 1 | |
Recruiting |
NCT05597735 -
Assessment of the Efficacy and Safety of Tecovirimat in Patients With Monkeypox Virus Disease
|
Phase 3 | |
Recruiting |
NCT05734508 -
Assessment of Safety Profile of MVA-BN Vaccine in the PALM-007 Study in DRC
|
Phase 4 | |
Active, not recruiting |
NCT05740982 -
A Phase 2 Randomized Multisite Trial to Inform Public Health Strategies Involving the Use of MVA-BN Vaccine for Mpox
|
Phase 2 | |
Recruiting |
NCT05947786 -
Mpox Paediatric and Adolescent Clinical Study
|
||
Recruiting |
NCT06045923 -
Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV
|
||
Completed |
NCT05476744 -
Viral Clearance and Epidemiological Characteristics in Patients With Monkeypox
|