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Pleth Variability Index (PVI) as a Measure of Volume Status During Transcatheter Mitral Valve Repair

Mitral Regurgitation Clinical Trial

Official title:
Pleth Variability Index (PVI) as a Measure of Volume Status During Transcatheter Mitral Valve Repair

Clinical Trial Summary

Transcatheter mitral valve repair in the form of MitraClip® is a safe and effective alternative to surgical mitral valve repair/replacement in patients with high operative morbidity and mortality risk. Successful MitraClip application depends on intraprocedural quantification of mitral regurgitation and left atrial pressure (LAP) monitoring. The pleth variability index (PVI) is a noninvasive, dynamic index based on analysis of the respiratory variations in the plethysmographic waveform recorded transcutaneously by the pulse oximeter. Studies demonstrate that PVI is accurate in predicting fluid responsiveness in mechanically ventilated adult patients. In this study, we wish to measure PVI during TMVR and correlate with invasive indices such as left atrial pressure (LAP) and stroke volume variation. Our study hopes to provide a real-time non-invasive alternative to invasive indices to better guide fluid management and improve hemodynamics.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03993938
Study type Interventional
Source Henry Ford Health System
Contact
Status Completed
Phase N/A
Start date October 1, 2019
Completion date June 1, 2021
View Details
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