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Clinical Trial Summary

This pilot study is a prospective, randomized clinical trial to evaluate the effect of anesthesia in the mitochondrial dysfunction patient.


Clinical Trial Description

Study subjects undergoing a routine medical care non-emergent procedure will be randomized into three different groups to receive one of the following anesthetic agents; Sevoflurane, Propofol or Dexmedetomidine.

The primary outcome of this pilot study is to evaluate and compare the incidence of adverse events in mitochondrial patients undergoing a diagnostic or therapeutic procedure up to 48 hours post anesthesia. The secondary outcome is to compare the metabolic derangements between three study groups by comparing changes in blood sugar, serum pH, serum bicarbonate, serum lactate and serum pyruvate levels before, during and after anesthesia in the groups. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02053766
Study type Interventional
Source The University of Texas Health Science Center, Houston
Contact Stephanie Maldonado
Phone 713-828-4291
Email Stephanie.Maldonado@uth.tmc.edu
Status Recruiting
Phase N/A
Start date January 10, 2014
Completion date September 2022

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