Mitochondria Inborn Errors of Metabolism and ANT Defects in Mitochondria Diseases

Mitochondrial Disease Clinical Trial

Official title:

Investigation of the Nature and Prevalence of Mitochondria Disease

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00786539
• Other study ID #: 20022608
• Status: Completed
• Start date: October 2006
• Est. completion date: May 2015

Study information

• Verified date: October 2022
• Source: University of California, Irvine
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The objective of this research protocol is to continue investigation of the nature and prevalence of mitochondria disease and to aid patients and health care providers in the understanding of these complex disorders.

This research study brings together many clinical sub-specialists to address the etiology of these disorders and to develop more effective approaches for their diagnoses and more reliable prognoses.

Description:

The non-invasive device named Diffuse Optical Spectroscopy developed at the Beckman Laser Institute is to be used to measure various physiological parameters. Since mitochondria produce most of the energy necessary for cellular function, their efficacy is most important for systems with a high energy demand like the brain, heart, skeletal muscle, kidney, liver, and endocrine tissues. As a result, mitochondria diseases usually manifest as complex, multi-organ disorders, requiring multispecialty investigations.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 18
• Est. completion date: May 2015
• Est. primary completion date: May 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 1 Day and older

Eligibility

Inclusion Criteria:

• Male or female all ages group with diagnosis of mitochondrial disorder

Exclusion Criteria:

• Subjects with visual, auditory and/or neurological problems known to result from toxic or environmental effects

Related Conditions & MeSH terms

• Mitochondrial Disease
• Mitochondrial Diseases

Intervention

Device:
• Diffuse Optical Spectroscopy
mitochondria

Locations

Country	Name	City	State
United States	Beckman Laser Institute Medical clinic	Irvine	California

Sponsors (2)

Lead Sponsor	Collaborator
University of California, Irvine	Beckman Laser Institute University of California Irvine

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Symptoms of Mitochondrial diseases		Up to 12 weeks