Missed Abortion Clinical Trial
Official title:
Sublingual vs Vaginal Misoprostol for Termination of First Trimesteric Missed Abortion
Verified date | August 2021 |
Source | Cairo University |
Contact | Ahmed Emam |
Phone | 01003304781 |
emam3882[@]gmail.com | |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Efficacy of sublingual versus vaginal misoprostol in termination of first trimester missed abortion
Status | Not yet recruiting |
Enrollment | 288 |
Est. completion date | October 16, 2021 |
Est. primary completion date | October 15, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 45 Years |
Eligibility | Inclusion Criteria: - Women with an ultrasound diagnosis of missed abortion < 13 weeks gestation without any clinical criteria of Inevitable abortion. Exclusion Criteria: - Patients refused the medical treatment. - Patients have contraindications of the drug (Misoprostol). - Missed abortion associated with any signs of sepsis |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Cairo University |
Allameh Z, Goharian M, Eslamian M. Effect of misoprostol with and without letrozole on the induction of abortion for women with first-trimester missed abortion. Int J Gynaecol Obstet. 2020 Nov;151(2):214-218. doi: 10.1002/ijgo.13326. Epub 2020 Sep 1. — View Citation
Tang OS, Gemzell-Danielsson K, Ho PC. Misoprostol: pharmacokinetic profiles, effects on the uterus and side-effects. Int J Gynaecol Obstet. 2007 Dec;99 Suppl 2:S160-7. Epub 2007 Oct 26. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The occurance of complete abortion within 24 hours with Misoprostol drug | Efficacy of sublingual and vaginal Misoprostol in complete termination of first trimester missed abortion | Within 24 hours | |
Primary | Which route is the best and less side effects in complete termination of first trimester missed abortion by Misoprostol drug | Vaginal versus sublingual route of administration of Misoprostol for complete termination of first trimester missed abortion | within 24 hours |
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