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Clinical Trial Summary

Aim of study Compare the success rate of misoprostol with versus without letrozole as a pretreatment for medical termination of pregnancy during the first trimester. Hypothesis: Letrozole value as a pre-treatment medication for misoprostol in induction of abortion during the first trimester. Research question: Will letrozole- misoprostol protocol give better results than misoprostol- alone protocol in induction of abortion during the first trimester?


Clinical Trial Description

Aim of the Work Compare the success rate of misoprostol with versus without letrozole as a pretreatment for medical termination of pregnancy during the first trimester. Hypothesis: Letrozole value as a pre-treatment medication for misoprostol in induction of abortion during the first trimester. Research question: Will letrozole- misoprostol protocol give better results than misoprostol- alone protocol in induction of abortion during the first trimester? Primary outcome: Complete abortion (complete expulsion of products of conception with no need for curettage) within one week from the first dose of misoprostol. Secondary outcome: • Curettage (surgical evacuation of the products of conception) - Incomplete abortion (retained products of conception). - Considerable bleeding that necessitates immediate evacuation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04593108
Study type Observational
Source Benha University
Contact
Status Active, not recruiting
Phase
Start date January 15, 2019
Completion date November 15, 2020

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