Clinical Trials Logo

Clinical Trial Summary

Analyze the behavioral response of patients with disorders of consciousness through olfactory stimulation, compare the response of olfactory stimulation in patients with different consciousness, and analyze the impact of olfactory stimulation on diagnosis; After the first, third, and sixth months of initial enrollment, the recovery of prognosis was tracked by the Coma Recovery Scale-Revision (CRS-R).


Clinical Trial Description

Previous studies suggested that olfactory stimulus have some effect on some patients with disorders of consciousness. Then, the aim of the present study is to know the prognostic value of olfactory stimulation and the diagnosis for DOC patients. DOC patients were recruited (standard diagnosis procedure is 5 times CRS-R testing within 10 days). The different stimuli were as follows: 1) 1-octene-3-ol, odor. 2) pyridine, odor. 3) water. We presented these stimuli randomly, and we recorded the patient's CRS-R scale behavioral response and response to olfactory stimulation. Analyze the behavioral response of patients with disorders of consciousness through olfactory stimulation, compare the response of olfactory stimulation in patients with different consciousness, and analyze the impact of olfactory stimulation on diagnosis; After the first, third, and sixth months of initial enrollment, the recovery of prognosis was tracked by the Coma Recovery Scale-Revision (CRS-R). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03732092
Study type Observational
Source Hangzhou Normal University
Contact
Status Completed
Phase
Start date March 15, 2018
Completion date December 15, 2019

See also
  Status Clinical Trial Phase
Completed NCT02288533 - Transcranial Direct Current Stimulation Effects in Patients With Chronic Consciousness Disorders N/A
Completed NCT03494218 - Reliability and Validity of the NCS (NCS-R)-Chinese Version N/A
Recruiting NCT02591069 - Vagal Nerve Stimulation in Coma Patients N/A
Active, not recruiting NCT03826407 - Development of a Point of Care System for Automated Coma Prognosis
Completed NCT04687553 - Validation of the Chinese Version of the SECONDs N/A
Completed NCT05536921 - Eye Tracking Technology in the Diagnosis of Neurological Patients
Completed NCT03126929 - Further Psychometric Data for the Reliability and the Diagnostic Validity of CRS-R N/A
Completed NCT03508336 - The Initiation of Swallowing Can Indicate the Prognosis of DOC
Completed NCT04921683 - The Use of LIFUP in Chronic Disorders of Consciousness N/A
Terminated NCT03367078 - tDCS in Patients With Disorder of Consciousness Due to Severe Acquired Brain Injury
Recruiting NCT04798456 - Aiming for a Better Understanding and Improvement of the Diagnosis and Prognosis of Patients With Disorders of Consciousness Through Multimodal Observations
Not yet recruiting NCT04248946 - Neural, Behavioural, and Clinical Effects of tDCS in PDOC; Feasibility Study N/A
Completed NCT01820923 - Transcranial Brain Stimulation in Vegetative State Patients N/A
Recruiting NCT01027572 - Thalamic Stimulation of Patients in Vegetative or Minimally Conscious State Phase 2
Completed NCT00557076 - The Efficacy of Familiar Voice Stimulation During Coma Recovery N/A
Recruiting NCT03910959 - Therapeutic Effects of Animal-assisted Therapy for Patients in a Minimally Conscious State N/A
Recruiting NCT04010838 - Spinal Cord Stimulation in Patients With Disorders of Consciousness N/A
Completed NCT04139239 - Diagnostic Accuracy of the Vegetative and Minimally Conscious State
Recruiting NCT03007784 - Two Intensities of Transcranial Direct Current Stimulation to Improve Consciousness in Severely Brain Injured Patients Phase 3
Not yet recruiting NCT02566720 - Amantadine and Functional Improvement Following ABI Measured by MRI Tractography; A Pilot Study N/A