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Clinical Trial Summary

The goal of this randomized controlled trial is to learn if Transcranial Pulse Stimulation (TPS) can improve cognitive functions in older adults with mild cognitive impairment (MCI). The study will also assess the safety of TPS. The main questions it aims to answer is: Does TPS improve cognitive functions such as global cognition, attention, memory, and executive function? Researchers will compare TPS to a sham control to evaluate the efficacy and safety of TPS in improving cognitive functions in older adults with MCI. Participants will: Be randomly assigned to receive either TPS or a sham intervention Undergo 6 sessions of TPS or sham intervention over a 2-week period Visit the clinic for cognitive assessments at 4 different time points (baseline, immediately post-intervention, 1-month follow-up, and 3-month follow-up) Complete questionnaires and undergo standardized neurocognitive tests, and/or MRI scans, and/or EEG assessments The study aims to provide insights into the potential therapeutic role of TPS in enhancing cognitive functions among older adults with mild cognitive impairment.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06407141
Study type Interventional
Source The University of Hong Kong
Contact Leung Pong Lee, BSocSc (Hons 1) MOT MPsyMed
Phone 64969335
Email dinollp@connect.hku.hk
Status Not yet recruiting
Phase N/A
Start date May 8, 2024
Completion date August 31, 2025

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