Home-Based Dual-Task Training for Older Adults

Mild Cognitive Impairment Clinical Trial

Official title:

Home-Based Dual-Task Training to Improve Function in Older Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05108246
• Other study ID #: STUDY00004857
• Secondary ID: UL1TR001412
• Status: Completed
• Phase: N/A
• Start date: September 1, 2021
• Est. completion date: December 31, 2022

Study information

• Verified date: June 2023
• Source: State University of New York at Buffalo
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This project is focused on conducting a home-based, thinking while moving exercise intervention for adults 65 years or older, who have mild cognitive impairment, that will integrate several effective training modalities including non-contact cardio-kickboxing, stepping exercise, balance/functional training, and muscle strengthening. Cognitive function, physical function, and dual-task abilities will be assessed over the 12-week intervention and comparisons will be made between participants in the exercise intervention and control participants receiving no intervention.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 18
• Est. completion date: December 31, 2022
• Est. primary completion date: December 31, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• 65 years or older
• Male or female
• Screened positive for mild cognitive impairment (Montreal Cognitive Assessment score 23 to 26 points
• Having no absolute contraindications to non-physician supervised exercise.

Exclusion Criteria:

• Lower-body amputation
• Non-English language speaker

Related Conditions & MeSH terms

• Cognitive Dysfunction
• Mild Cognitive Impairment

Intervention

Behavioral:
• Dual-Task Exercise Training
Simultaneous cognitive-motor training

Locations

Country	Name	City	State
United States	University at Buffalo, SUNY	Buffalo	New York

Sponsors (2)

Lead Sponsor	Collaborator
State University of New York at Buffalo	National Center for Advancing Translational Sciences (NCATS)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in Cognitive Function (Interference inhibition and attention)	Change in performance on the Stroop Color-Word Interference Test	baseline, 6 week, 12 weeks
Primary	Change in Cognitive Function (Task-switching and attention)	Change in performance on the Trail-Making Test Sections A and B	baseline, 6 week, 12 weeks
Primary	Change in Walking Ability, Lower-Body Strength, and Balance	Change in performance on the Short Physical Performance Battery	baseline, 6 weeks, 12 weeks
Secondary	Change in Dual-Task Performance	Change in the Timed Up and Go Test: Dual Task (single condition, motor condition, and cognitive condition	baseline, 6 week, 12 weeks