Mild Cognitive Impairment Clinical Trial
— NeurofeedelOfficial title:
SMR/Theta Neurofeedback Training Improves Cognitive Performance and EEG Activity in Elderly With Mild Cognitive Impairment: A Pilot Study
Verified date | February 2019 |
Source | Broca Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This is a non-pharmacological pilot study showing the improvement of a SMR/theta neurofeedback training program on cognitive performance and EEG activity in Elderly with Mild Cognitive Impairment.
Status | Completed |
Enrollment | 20 |
Est. completion date | December 15, 2018 |
Est. primary completion date | December 15, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 65 Years to 90 Years |
Eligibility |
Inclusion Criteria: - Clinical diagnosis of Mild Cognitive Impairment - education level of 9 years of studies minimum - righthandedness - subjective memory complaint confirmed by an informant - a Mini Mental Status Examination score >20. - preserve activity of daily living and absence of dementia. Exclusion Criteria: - elderly persons who were under guardianship - resident in nursing facilities - neurological disease, psychiatric disease - and involved in another cogniitve intervention. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Fabienne Marlats |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Rey Auditory Verbal Learning test | Assessment of verbal learning in episodic memory, evaluating the ability to encode, combine, store and long-term consolidation process. | Assessment at baseline, change from baseline to 11 weeks immediately after the NF training and 1 month follow-up | |
Secondary | Relative power for delta, theta, alpha, sensorimotor and lower beta frequency bands. | Electroencephalography was recorded and EEG power spectrum was calculated using the fast Fourier transform. The power spectral density was calculated to extract the relative power for each frequency band and estimated as a log-ratio. | Assessment at baseline, change from baseline to 11 weeks immediately after the NF training and 1 month follow-up |
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