Mild Cognitive Impairment Clinical Trial
Official title:
A Cognitive Training Tool Based on Life-logging in Mild Cognitive Impairment (ReMemory-MCI)
Background: Mild Cognitive Impairment (MCI) is a risk factor for dementia and represents a
critical window of opportunity to intervene and alter the trajectory of both cognitive and
functional decline. Emerging life-logging technologies has shown a tremendous potential to
increase autobiographical memory.
Objective: The main goal of the present study is to develop a Cognitive Training program (CT)
for MCI based on life-logging captured by a Wearable Camera (WeC) recording specific
autobiographical episodes for stimulating posteriorly episodic memory. The challenge is to
create an application to manage this large collection of images, which can be easily
retrieved as events by users in a therapeutic context as a multimodal cognitive stimulation.
The investigators will conduct a quasi-experimental design with non-equivalent control group,
evaluating the effectiveness of the life-logging re-experiencing program immediately and
3-month follow-up period.
Methodology: The design is a pretest, posttest and follow-up design, where 30 adults with MCI
were sequentially allocated to one of two conditions: intervention or control group. All
subjects wore a lifelogging WeC during two weeks, and subsequently they were generated
several videos with the most relevant information of each event. Subjects in the Intervention
Group will attend 1-hour individual training sessions 2 times per week for 14 8 weeks. Main
outcomes measures will be cognitive, functional, emotional and quality of life measures, as
well as biochemical measures (BDNF).
Expected results: The investigators expect the outcomes to provide preliminary evidence that
autobiographical experimentation CT programs can positively impact cognitive functioning and
may represent an effective strategy to improve memory and functionality in those who begun to
experience cognitive decline.
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