Mild Cognitive Impairment Clinical Trial
Official title:
The Development and Evaluation of the Effectiveness of a Virtual Interactive Memory Training Program for Older Adults With Mild Cognitive Impairment: Protocol of a Randomized Controlled Study
Verified date | December 2017 |
Source | Ministry of Science and Technology, Taiwan |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study sought to investigate the changes in objective memory performance (including immediate recall and delayed recall), subjective memory complaints and degree of depression in older adults with mild cognitive impairment after Virtual interactive memory training (VIMT).
Status | Completed |
Enrollment | 60 |
Est. completion date | December 2017 |
Est. primary completion date | December 2017 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 65 Years and older |
Eligibility |
Inclusion Criteria: 1. Participants must endorse at least two items from a list of frequent subjective memory complaints by patient and/or an informant 2. Objective memory impairment on neuropsychological tests of memory 1.5 SD or more below age/education norms 3. Clinical neurologic examination by the Mini-Mental State Examination (MMSE) score of 24 or higher, and cut-off score of 23/24 on the Montreal Cognitive Assessment (MoCA) 4. No impairment in personal activities of daily living (P-ADL) as determined by clinical interview with participant and family Exclusion Criteria: 1. The clinical diagnosis of dementia was based on the DSM-IV-TR 2. Active in another cognitive or memory-related training in the past year 3. Comorbid medical conditions that would predispose them to imminent functional decline or cognitive impairment 4. A diagnosis of major neurological or psychiatric illness history and/or behavioral problems that would sufficiently impair performance to make participation impossible 5. Severe losses in vision, hearing, or communicative ability |
Country | Name | City | State |
---|---|---|---|
Taiwan | Residential care facilities | Taipei |
Lead Sponsor | Collaborator |
---|---|
Ministry of Science and Technology, Taiwan |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in objective memory performance as measured by the Chinese version of the Wechsler Memory Scale-III (WMS-III). | Change from baseline in objective memory performance at Immediate post-test, 3 months, 6 months and one year after intervention. | ||
Secondary | Change in subjective memory complaints as measured by the Multifactorial Memory Questionnaire (MMQ). | Change from baseline in subjective memory complaints at Immediate post-test, 3 months, 6 months and one year after intervention. |
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