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A Study of Fesoterodine and Oxybutynin on Cognitive Function in Mild Cognitive Impairment

Mild Cognitive Impairment Clinical Trial

Official title:
A Double Blind, Randomized Four Way Cross Over Study to Compare the Effect of Fesoterodine 4mg and 8mg Once Daily and Oxybutynin 5mg Twice Daily After Steady State Dosing Versus Placebo on Cognitive Function in Subjects With Overactive Bladder, Over the Age of 75 Years With Mild Cognitive Impairment

Clinical Trial Summary

The purpose of this study is to assess the effects of fesoterodine at 4mg and 8mg doses versus a placebo and oxybutynin 5mg bid versus placebo on cognitive abilities in older people with overactive bladder and mild cognitive impairment.

Clinical Trial Description

This is a randomized placebo controlled, blinded four way cross over trial of the effect of medications used to treat overactive bladder on the cognition of older men and women with mild cognitive impairment. Each treatment phase is a week, with a weeks washout period before starting the next treatment. Cognitive testing is by way of a validated computer assisted battery of tests ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02240459
Study type Interventional
Source University of Alberta
Contact
Status Completed
Phase Phase 2
Start date August 2016
Completion date January 31, 2020
View Details
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