Mild Cognitive Impairment Clinical Trial
NCT number | NCT02225964 |
Other study ID # | XuanwuH 2 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | January 2014 |
Est. completion date | December 2018 |
Verified date | June 2020 |
Source | Xuanwu Hospital, Beijing |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This study is to find out the imaging marker and the changing laws of the marker during the course of the disease. The final purpose is to provide scientific evidence for new prevention, diagnosis and treatment of Alzheimer's disease.
Status | Completed |
Enrollment | 200 |
Est. completion date | December 2018 |
Est. primary completion date | December 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Complaint about memory loss and confirmed by an informant - Cognitive impairment in single or multiple domains, adjusted for age and education - Normal or near-normal performance on general cognitive function and no or minimum impairment of daily life activities - A Clinical Dementia Rating (CDR) score is 0.5 - Failure to meet the criteria for dementia - Carrying susceptible gene APOEe4 - Must be able to accept examination of MRI, sight and hearing allow to complete test Exclusion Criteria: - Other diseases that cause cognitive impairment,such as thyroid disease,stroke and so on - people who have severe visual and hearing impairment |
Country | Name | City | State |
---|---|---|---|
China | Department of Neurolgy,Xuanwu Hospital of Capital Medical University | Beijing | Beijing |
Lead Sponsor | Collaborator |
---|---|
XuanwuH 2 | Xuanwu Hospital, Beijing |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | the conversion of aMCI patients with APOEe4 to AD | According to situation of the conversion or non-conversion and differences in the conversion progression, we will analyze the data between the inter-groups and intra-groups, compare the imaging data of baseline and follow-up, find the prediction imaging marker of AD and optimize the reliability and validity. | one year |
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