Mild Cognitive Impairment Clinical Trial
Official title:
The Effects of Omega-3 Fatty Acids Monotherapy in Alzheimer's Disease and Mild Cognitive Impairment: a Preliminary Randomized Double-Blind Placebo-Controlled Study
This preliminary study is aimed to investigate whether it is feasible to conduct a study to
use fish oil compared to the placebo(olive oil) in people with cognitive impairment. We will
also explore whether fish oil has better efficacy in some clinical aspects in people with
cognitive impairment during 24 weeks intervention. The major clinical outcome will be:
1. general clinical impression
2. cognitive function
Despite some positive findings from observational and animal studies, the effects of n-3 PUFA administration on cognitive impairment in humans have received little evaluation to date. Although some clinical trials of fish oil have been reported, the results are inconsistent. Given these inconsistent findings, we carried out a preliminary study to investigate the effect of fish oil monotherapy on cognitive function and general clinical condition in patients with cognitive impairment. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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