Migraine Clinical Trial
Official title:
Basic Research on Acetazolamide´s Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow in a Humane Experimental Headache Model
In this study the investigators will research the hypothesis that the drug Acetazolamide induce headache and dilation of cerebral arteries and increase the cerebral blood flow in the areas of the brain supplied by these arteries.
To investigate headache score and accompanying symptoms during and after infusion of
acetazolamide.
With magnetic resonance imaging the investigators will investigate changes in regional
cerebral blood flow (rCBF) in the area supplied by middle cerebral artery (MCA), diameter of
MCA, the Internal carotic artery (ICA), the superficial temporal artery (STA) and the Medial
Meningeal artery (MMA).
;
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science
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