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Clinical Trial Summary

Investigators hypothesize that chronic primary headaches are accompanied by a discrete pattern of brain metabolism and activity involving brain structures related to the development of acute exacerbations as well as pain modulation. Such structures include the brainstem, hypothalamus, and orbitofrontal cortex and can be defined using functional brain imaging.


Clinical Trial Description

Specific aims of the study include:

1. To determine the pattern of brain metabolism using positron emission tomography (PET) found in chronic migraine, episodic migraine and control patients.

2. To determine changes of resting state brain networks using magnetic resonance imaging (MRI) between patients with chronic or episodic headache and healthy volunteers. ;


Study Design

Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT01741246
Study type Observational
Source University of California, San Francisco
Contact
Status Completed
Phase N/A
Start date September 2011
Completion date June 2015

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