Acupuncture for Migraine: a Functional Magnetic Resonance Imaging (fMRI) Study

Migraine Clinical Trial

Official title:

Acupuncture Treatment for Migraine: a Functional Magnetic Resonance Imaging Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01152632
• Other study ID #: 30930112/C190301
• Status: Completed
• Phase: N/A
• First received: June 27, 2010
• Last updated: November 25, 2014
• Start date: January 2010
• Est. completion date: December 2013

Study information

• Verified date: August 2012
• Source: Chengdu University of Traditional Chinese Medicine
• Contact: n/a
• Is FDA regulated: No
• Health authority: China: National Natural Science Foundation
• Study type: Interventional

Clinical Trial Summary

Selecting acupoints along meridians is the predominant principle in acupuncture treatment, and it is also considered to ensure acupuncture efficacy. This experiment is to investigate whether specific brain networks gradually come in formation in accordance with this kind of acupoint selection methods.

Description:

Every participants in the four intervention groups will go through functional magnetic imaging (fMRI) scan four times: the 1st scan will be performed at their baselines; the 2nd scan will be done after 2 courses (10 times) acupuncture treatment; the 3rd scan will be performed when the 4 courses end; the 4th scan will be operated after three-month enrollment.

Volunteers in waiting list group will undergo the above scans at the same time points in exception of acupuncture treatment.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: December 2013
• Est. primary completion date: June 2013
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 17 Years to 45 Years

Eligibility

Inclusion Criteria:

• clinical diagnosis of non-aura Migraine formulated by the international headache society in 2004

Exclusion Criteria:

• people with other types of headache

• people with organic cerebral disorders

• people with primary disorders

• people in moderate or severe anxiety or depression

• people in pregnancy

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Migraine
• Migraine Disorders

Intervention

Other:
• manual acupuncture
thirty minutes duration every time, five times per week for one course, a total four courses

Locations

Country	Name	City	State
China	Chengdu University of Traditional Chinese Medicine	Chengdu	Sichuan

Sponsors (1)

Lead Sponsor	Collaborator
Chengdu University of Traditional Chinese Medicine

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	improvement of headache frequency		4 weeks	No