Migraine Headaches Clinical Trial
Official title:
A Randomized, Double-Blind, Cross-Over, Placebo-Controlled Study to Determine the Efficacy and Safety of ELS-M11 in Acute Migraine
This is a Phase 1/ Phase 2, 12-week, multi-center, randomized, double-blind, cross-over,
placebo-controlled study to evaluate the efficacy and safety of ELS-M11 compared to placebo
in 50 male and female subjects, aged 18 to 65 years that suffer recurring moderate-severe
migraine headaches (2-8 per month).
This study is designed to describe the efficacy and safety of ELS-M11 as compared to placebo.
Achelios is developing ELS-M11 for topical application for the acute treatment of migraine
events in patients with a history of migraine with or without aura.
To be eligible for the study, patients must have a one-year documented history of migraine
headache (as defined by the International Headache Society IHS), with or without aura, with
2≤8 moderate or severe migraine attacks per month in the 2 months prior to the screening
visit.
The total duration of the study is the completion of five migraine headaches per subject over
a maximum 12 week period followed by a 3-14 day Follow-Up Period.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT06342232 -
The Efficacy of Neurofeedback Mindfulness in Migraine Management
|
N/A | |
| Completed |
NCT02351544 -
Prospective, Multi-Center Evaluation of the Efficacy of Peripheral Trigger Decompression Surgery for Migraine Headaches
|
N/A | |
| Completed |
NCT00665236 -
Craniosacral Therapy in Migraine: A Feasibility Study
|
N/A | |
| Completed |
NCT01706003 -
The Utility of Telemedicine in the Management of Migraine
|
||
| Terminated |
NCT01944059 -
Theramine® in the Prevention of Migraine Headache
|
Phase 4 | |
| Terminated |
NCT01629329 -
Prochlorperazine Versus Acetaminophen, Aspirin, and Caffeine for the Treatment of Acute Migraine
|
Phase 4 | |
| Completed |
NCT00792636 -
A Study to Determine the Effect of Sumatriptan and Naproxen Sodium Combination Tablet, Sumatriptan Tablet, and Naproxen Sodium Tablet on Blood Pressure When Treating Migraine Headaches That Occur During a 6-month Period
|
Phase 4 | |
| Not yet recruiting |
NCT05536635 -
Effect of Breathing Techniques on Migraine Attacks and Severity
|
N/A | |
| Completed |
NCT00442221 -
The Safety Of Combo Formulation In The Treatment Of Multiple Episodes Of Acute Migraine Over 12 Months
|
Phase 3 | |
| Completed |
NCT00109083 -
A Study of the Efficacy of RWJ-333369 in the Prevention of Migraine
|
Phase 2 | |
| Completed |
NCT02098499 -
Haldol/Diphenhydramine Versus Metoclopramide/Diphenhydramine for Treatment of Acute Headache in the Emergency Department: A Randomized Controlled Trial
|
Phase 4 | |
| Completed |
NCT00714727 -
Set Point Acupuncture for Migraines Using a Digital Assistant
|
Phase 1 | |
| Completed |
NCT00434083 -
To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migrane Headaches
|
Phase 3 | |
| Completed |
NCT00960245 -
Relative Bioavailability Study of Nadolol (1 x 80 mg) Tablets Under Fasting Conditions
|
Phase 1 | |
| Completed |
NCT02856802 -
An Efficacy and Safety Study of DFN-02 (Sumatriptan Nasal Spray 10 mg)
|
Phase 2 | |
| Completed |
NCT00355056 -
PREMIUM Migraine Trial
|
N/A | |
| Completed |
NCT01118988 -
Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
|
N/A | |
| Completed |
NCT00433732 -
To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migraine Headaches
|
Phase 3 | |
| Completed |
NCT00750594 -
Patent Foramen Ovale in Children With Migraine Headaches
|
N/A |