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Pharmacokinetic Study of Rituximab Induction Regimen in ANCA-associated Vasculitis — MONITUX  

Microscopic Polyangiitis Clinical Trial

Official title:
Pharmacokinetic Study of Rituximab Induction Regimen in ANCA-associated Vasculitis : a Predictive Factor of Clinical Outcome? (MONITUX)

Clinical Trial Summary

The aim of the investigators' study is to evaluate whether monitoring serum rituximab levels could be an interesting tool in the follow-up of ANCA-associated vasculitis patients. All consecutive patients, hospitalized for a new diagnosis of ANCA-associated vasculitis or the relapse of a known ANCA-associated vasculitis, in which the decision to start an induction regimen with rituximab has been taken, will be included. Serum rituximab levels (along with serum anti-rituximab antibodies levels) will be determined (at M+1 and M+3) and the correlation with clinical outcome at M+6 will be analyzed.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02474888
Study type Observational
Source Centre Hospitalier Universitaire de Saint Etienne
Contact
Status Terminated
Phase
Start date September 15, 2015
Completion date June 12, 2020
View Details
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