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Efficacy and Safety of Oral Rifaximin in Patients With Active Microscopic Colitis

Microscopic Colitis Clinical Trial

Official title:
Efficacy and Safety of Oral Rifaximin in Patients With Active Microscopic Colitis

Clinical Trial Summary

This is an open label study looking at rifaximin therapy for the treatment of microscopic (collagenous or lymphocytic) colitis.

Clinical Trial Description

This is an open-label single-arm trial to evaluate the efficacy of Rifaximin in patients with active microscopic colitis (MC). 10 subjects will be asked to take 500mg Rifaximin three times per day for 4 weeks. The primary endpoints will be histologic response and clinical remission (less than 3 stools per day and less than 1 watery stool per day within the prior 7 days. The secondary endpoint will be change of the MC Disease Activity Index (MCDAI). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04043897
Study type Interventional
Source NorthShore University HealthSystem
Contact Daniel Amusin, BS
Phone 847-570-3558
Email damusin@northshore.org
Status Recruiting
Phase Phase 2
Start date June 29, 2018
Completion date December 2021
View Details
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