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Clinical Trial Summary

Ascitic fluid microbiome is going to be investigated in this study by using internal transcripted spacer (ITS) and 16S ribosomal RNA (rRNA) polymerase chain reaction (PCR) and sequencing as conventional culture methods are lacking sensitivity regarding diagnosis of spontaneous bacterial peritonitis (SBP). All patients with routinely performed ascitic fluid puncture and underlying liver cirrhosis are included in this study. Next generation sequencing (NGS) in ascitic fluid, skin swaps from puncture side and stool samples as well as conventional culture methods are performed to investigate the difference in the microbiome between patients with and without SBP.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02813590
Study type Observational
Source Medical University of Graz
Contact
Status Withdrawn
Phase
Start date June 2016
Completion date September 2017

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