Microbiome Clinical Trial
Official title:
Randomized Double-Blind Study of the Cosmetic Effects of Topical Acetyl Zingerone
Cosmeceuticals are an emerging market within dermatology and the growth of natural products and derivatives of natural products has accelerated in use within the field. Here the investigators aimed to study the microbial and cosmetic effects of Synoxyl AZ, the trade name for topical acetyl zingerone (AZ), a novel compound designed based on Zingerone and curcumin.
Cosmeceuticals are an emerging market within dermatology and the growth of natural products
and derivatives of natural products has accelerated in use within the field. Here the
investigators aim to study Synoxyl AZ, the trade name for topical acetyl zingerone (AZ), a
novel compound designed based on Zingerone and curcumin.
Both curcumin and Zingerone are from the Zingiberacea family of plants (also known as the
ginger family). Both have been widely studied and noted to have antibacterial effects and
promote skin health effects. Curcumin has been studied widely in recent years due to various
microbial effects. AZ is a derivative that is similar to both Zingerone and curcumin and has
been noted to have many different activities including anti-inflammatory, antimicrobial, and
antioxidant functions. However, there are no studies looking at how it modulates the skin
cosmetically or the superficial microbiome.
The aim of this study was to compare the cosmetic effects of AZ to a vehicle over an 8-week
period.
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