Microbiome Clinical Trial
Official title:
A Single Center, Five Week, Evaluator Blinded, Clinical Trial Evaluating Two Cleansing and/or Moisturizing Regimens on the Skin of Healthy Infants Using Clinical, Instrumental, D-Squame Tape, Microbiome and Parental Assessments
This study is to assess the impact of two skincare regimens on the cutaneous microbiome and skin physiology of healthy male and female infants, ages 3-6 months using clinical, instrumental, D-Squame tape, microbiome and parental assessments over a five-week period.
Skin cleansing has been demonstrated as a simple strategy to help keep skin healthy. There
are many types of cleansing and moisturizing routines that have been shown to have different
effects on the skin barrier such as reducing sebum and exogenous contaminants, controlling
odors, and affecting the skin microbiome.1 A previous study in an adult population showed
that use of a mild surfactant cleanser had less of an impact on the skin barrier than a
liquid castile soap (data on file ).2 Because infant skin differs from an adult's in
structure, function, and composition3, cleanser and/or lotion regimens may impact the skin
barrier of infants differently.
There is very little information in the literature on how the use of product regimens impacts
the cutaneous microbiome and skin physiology of adults1 and even less about how it impacts
the skin of children.
This study will explore the impact that the use of two regimens - one cleansing and the other
cleansing and moisturizing - has on the holistic skin barrier of infants ages 3-6 months.
The IPs are a baby wash and a baby lotion, which are both cosmetic body products. The
auxiliary product is a commercially available, cosmetic baby body wash.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT03586622 -
One Year Home Monitoring and Treatment of IBS Patients
|
N/A | |
| Active, not recruiting |
NCT04552834 -
Alterations of the Microbiome During Critical Illness With Short and Long Term Clinical Outcomes
|
||
| Completed |
NCT03201068 -
Probiotic Supplement and Microbiome, Immune System and Metabolic Syndrome
|
N/A | |
| Completed |
NCT04217122 -
Effect of Strawberry Consumption on the Microbiome
|
N/A | |
| Recruiting |
NCT05521295 -
Frozen Embryo Transfer Pregnancy Outcomes Prediction by Microbiome
|
||
| Recruiting |
NCT05545631 -
Frozen Embryo Transfer Pregnancy Outcomes Prediction by Microbiome and Transcriptome
|
||
| Not yet recruiting |
NCT05852145 -
Oral Changes With Caloric and no Caloric Sweeteners
|
Phase 1/Phase 2 | |
| Withdrawn |
NCT04099446 -
A Non-Interventional Pilot Study to Explore the Skin Microbes in Skin Cancer
|
||
| Recruiting |
NCT05445544 -
A Multicenter Cohort Study on Maternal and Infant Microecology and New Targets for Pre-eclampsia Screening in China
|
||
| Active, not recruiting |
NCT03213275 -
The Premature Gut Microbiome and the Influence on Neonatal Immunity, Brain Development and White Matter Injury
|
||
| Recruiting |
NCT05505110 -
MOdification Of THe Early-Life Respiratory Microbiome Through Vaginal SEEDing
|
N/A | |
| Completed |
NCT04851340 -
Investigating the Detection of Bovine and Soy Proteins in Human Milk
|
N/A | |
| Completed |
NCT06133400 -
Mapping the Health Status of the Population of French Polynesia: the MATAEA Project
|
N/A | |
| Withdrawn |
NCT04114513 -
Dietary Fibers Effect on the Gut Microbiota Composition
|
N/A | |
| Not yet recruiting |
NCT05612620 -
Elucidating the Microbiome in Patients With Recurrent Pregnancy Loss
|
||
| Completed |
NCT04611945 -
Westlake Sailing Cohort
|
||
| Recruiting |
NCT04260295 -
Study of the Correlation of Tumor Tissue Microbiome to the Pathogenesis of Lung Cancer
|
||
| Completed |
NCT04155684 -
Dysbiosis Impact on Lung Disease in HIV
|
||
| Active, not recruiting |
NCT06424691 -
Infant Restore: Efficacy of Microbiome Analysis and Education
|
N/A | |
| Completed |
NCT05510050 -
Comparison Study of Manapol and DaltonMax on Immune Function, Microbiome, and Related Variables in Men and Women
|
N/A |