The Relationship Between Microbiota and Coronary Ectasia

Microbial Disease Clinical Trial

Official title:

The Evaluation of the Relationship Between Coronary Ectasia And Trimethylamine N Oxide

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06384703
• Other study ID #: 201518015
• Status: Completed
• Start date: November 3, 2020
• Est. completion date: June 18, 2021

Study information

• Verified date: May 2021
• Source: Konya Beyhekim Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Introduction: It is now known that the microbiota is far beyond the microbial communities living in certain parts of our body and functions like a metabolic organ. In addition, the microbiota, through its metabolites, is involved in the pathophysiology or progression of a wide range of diseases, from atherosclerotic diseases to metabolic diseases and even neurological diseases. Among these metabolites, trimethylamine n-oxide metabolite has been shown to be particularly effective on atherosclerotic heart diseases.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 2
• Est. completion date: June 18, 2021
• Est. primary completion date: April 25, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• over 18 years old

• not having occlusive coronary artery disease

• having coronary ectasia

Exclusion Criteria:

• patients with chronic kidney disease,

• revascularized coronary artery disease,

• previously documented critical coronary stenosis,

• acute or chronic inflammatory disease,

• rheumatologic disease,

• known active malignant disease,

• heart failure,

• moderate-to-severe valvular pathology

• patients who were on any steroid or immunosuppressive therapy

Related Conditions & MeSH terms

• Microbial Disease

Intervention

Diagnostic Test:
• Taking blood for kit study
Taking blood for kit study (Elisa kit)

Locations

Country	Name	City	State
Turkey	Necmettin Erbakan University	Konya

Sponsors (2)

Lead Sponsor	Collaborator
Konya Beyhekim Training and Research Hospital	Necmettin Erbakan University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	death	Death from any cause within the last month	1 month