MGMT-Unmethylated Glioblastoma Clinical Trial
Official title:
Anlotinib Combined With STUPP Protocol as First-line Regimen for MGMT Nonmethylated Glioblastoma: a Multicenter, Open-label, Single-arm, Phase II Clinical Trial
The purpose of this study is to test the efficacy and safety of Anlotinib in combination with STUPP regimen for MGMT promoter nonmethylated glioblastoma.
For MGMT unmethylated glioblastoma patients undergoing STUPP regimen adjuvant therapy, during adjuvant chemotherapy, concurrent with anti-angiogenesis targeted therapy(Anlotinib capsule,d1-14). ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05033587 -
Study of AK105 With Anlotinib and Radiotherapy Adjuvant Therapy in MGMT Unmethylated Newly Diagnosed Glioblastoma.
|
Phase 2 | |
Active, not recruiting |
NCT04396860 -
Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma
|
Phase 2/Phase 3 | |
Recruiting |
NCT05879250 -
WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
|
Phase 2 | |
Recruiting |
NCT06186401 -
Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells
|
Phase 1 | |
Terminated |
NCT03250299 -
Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
|
Phase 1 | |
Recruiting |
NCT03107780 -
Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer
|
Phase 1 | |
Recruiting |
NCT05909618 -
Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases
|
Phase 2 | |
Not yet recruiting |
NCT05694416 -
Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma
|
Phase 2 | |
Recruiting |
NCT04224441 -
Repurposing Chlorpromazine in the Treatment of Glioblastoma
|
Phase 2 | |
Recruiting |
NCT05236036 -
Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma
|
Phase 1 | |
Active, not recruiting |
NCT03452930 -
Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma
|
Phase 1 |