Methemoglobinemia After Liposuction - Diagnostic by Pulse Oximetry and Blood Gas Analysis.

Methemoglobinemia Clinical Trial

Official title:

Methemoglobinemia After Liposuction Under Tumescent Local Anesthesia - Timecourse and Diagnostics by Pulse Oximetry and Blood Gas Analysis.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01766999
• Other study ID #: MetHb02
• Status: Completed
• Start date: August 2008
• Est. completion date: December 2010

Study information

• Verified date: November 2020
• Source: University Hospital Schleswig-Holstein
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Tumescent local anesthesia is a procedure which is frequently performed for plastic cosmetic surgical procedures such as liposuction. The subcutaneous adipose tissue is infiltrated with large volumes of a solution which also contain local anesthetics. However local anesthetics, can also lead to a marked production of methemoglobin. New generation pulse oximeters are able to measure SpMetHb non-invasivly.

The aim of this study is:

1. to investigate multi-wavelength pulse oximetry as a monitoring method for patients at increased risk for methemoglobinemia.

2. to illustrate MetHb concentrations over a course of 24 hours after a liposuction employing tumescent anesthesia has been carried out.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 133
• Est. completion date: December 2010
• Est. primary completion date: May 2009
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 99 Years

Eligibility

Inclusion Criteria:

• planned liposuction in tumescent local anesthesia

Exclusion Criteria:

• hematologic disorders

Related Conditions & MeSH terms

• Methemoglobinemia

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital Schleswig-Holstein

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlation between hemoximetric and pulseoximetric measured methemoglobin		24 hours
Secondary	Time course of MetHb concentration following liposuction employing tumescent anesthesia.		24 hours