Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)

Methamphetamine Abuse Clinical Trial

Official title:

Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05700994
• Other study ID #: PEER-CM
• Status: Recruiting
• Phase: N/A
• Start date: November 13, 2023
• Est. completion date: September 30, 2026

Study information

• Verified date: March 2024
• Source: Oregon Health and Science University
• Contact: Todd Korthuis, MD, MPH
• Phone: 503494-8044
• Email: korthuis[@]ohsu.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The main goal of this study is to tests the effect of incentivizing achievement of self-identified, personal harm reduction goals (Contingency management or CM) compared with standard of care (peer harm reduction service with incentives for peer visits) to increase the reach and effectiveness of methamphetamine (MA) harm reduction services.

Description:

Using a hybrid type 1 effectiveness-implementation framework and stepped-wedge design, this study will randomize eighteen community-based peer harm reduction sites to provide contingency management incentives for achieving self-identified harm reduction goals set with peer specialists using a participant-driven harm reduction goal-setting process (e.g. completing overdose prevention and supply training, daily life goals, treatment and care goals, relationship and social support goals) versus standard of care contingency management (i.e. incentives for peer encounter attendance).

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 1800
• Est. completion date: September 30, 2026
• Est. primary completion date: June 30, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 105 Years

Eligibility

Inclusion Criteria:

This intervention is at the site level. Community-based organization sites are eligible if they:

• Use peer support specialists to provide direct outreach and harm reduction services to people who use drugs

• Are willing to be trained in the two strategies for peer-facilitated contingency management

De-identified administrative data is used to identify an analytic sample of clients who:

• Reported past 30-day methamphetamine use at community-based organization intake.

Exclusion Criteria:

Community-based organization sites who:

• Do not use peer support specialists to provide direct outreach and harm reduction services to people who use drugs

• Are not willing to be trained in the two strategies for peer-facilitated contingency management

Related Conditions & MeSH terms

• Methamphetamine Abuse

Intervention

Behavioral:
• Peer Contingency Management
Participants allocated to peer-facilitated contingency management will receive incentives for achieving self-identified harm reduction goals set with peer specialists using a participant-driven harm reduction goal-setting process (e.g. completing overdose prevention and supply training, daily life goals, treatment and care goals, relationship and social support goals)
• Standard of Care Contingency Management
Participants allocated to standard of care contingency management will receive incentives for peer encounters.

Locations

Country	Name	City	State
United States	Comagine Health	Portland	Oregon
United States	Oregon Health & Science University	Portland	Oregon

Sponsors (3)

Lead Sponsor	Collaborator
Oregon Health and Science University	Comagine Health, Oregon Health Authority

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of participants who overdose	Test the impact of incentives for achieving self-identified, personal harm reduction goals on the likelihood of overdose among people using methamphetamine at 6 months from enrollment identified through completed assessment.	6 months from baseline
Primary	Number of participants who achieve self-identified goals	Determine whether incentives for achieving self-identified, personal harm reduction goals increases engagement with harm reduction services at 6 months from enrollment identified through completed assessment.	6 months from baseline
Primary	Number of participants who engage in substance use disorder treatment	Determine whether incentives for achieving self-identified, personal harm reduction goals increases engagement with treatment services at 6 months from enrollment identified through completed assessment.	6 months from baseline