Clinical Trials Logo
  1. Home
  2. Metformin
  3. NCT01237522

A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers

Metformin Clinical Trial

Official title:
A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers.

Clinical Trial Summary

The aim of the study is to evaluate the pharmacokinetics of metformin in healthy Caucasians volunteers with and without the polymorphism A270S in OCT2,thus the study hypothesis is that renal clearance of metformin is affected in Caucasian with the known single nucleotide polymorphisms A270S in OCT2.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Health Services Research

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01237522
Study type Interventional
Source University of Southern Denmark
Contact
Status Completed
Phase Phase 4
Start date August 2010
Completion date December 2010
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05052918 - The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes N/A
Recruiting NCT05469659 - Effect of Tofogliflozin on UACR Compared to Metformin Hydrochloride in Diabetic Kidney Disease (TRUTH-DKD) Phase 2
Completed NCT00767351 - Variation in Serum Levels of Metformin in Patients With Reduced Renal Function
Recruiting NCT06126029 - Effect of Metformin as Add-on Therapy to Ibuprofen on Disease Activity in Knee Osteoarthritis Patients. Phase 2
Enrolling by invitation NCT05900284 - Safety and Feasibility of Metformin for Sepsis Induced AKI Phase 2
Enrolling by invitation NCT06125587 - Chiglitazar/Metformin in Non-obese Women With PCOS Phase 2/Phase 3
Not yet recruiting NCT05013112 - Ameliorating Metabolic Profiling After Kidney Transplantation (AMPKT) N/A
Recruiting NCT03525028 - A Clinical Trial of Metformin to Decrease Glucocorticoids Side Effects in Patients With Autoimmune Uveitis N/A
Recruiting NCT05680805 - Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS Phase 4
Not yet recruiting NCT05532813 - Evaluation of the Efficacy and Safety of Metformin in the Myotonic Dystrophy Type 1 (Steinert's Disease) Phase 3
Recruiting NCT06325956 - PCOS Immune Function Predicts Metformin Efficacy N/A
Recruiting NCT06325969 - PCOS Patients Immune Status Evaluation
Completed NCT03335423 - Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions Phase 1
Recruiting NCT04477590 - Interactions of Medicine and Exercise With Meal Timing N/A
Not yet recruiting NCT06459310 - Pilot Study on Evaluating the Geroprotective Effect of Metformin Phase 2
Not yet recruiting NCT05412056 - Metformin to Prevent Preterm Birth in Twin Pregnancy Phase 2/Phase 3
Terminated NCT01756105 - Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women Phase 2
Completed NCT04377451 - Metformin in Dengue With Obesity Phase 1/Phase 2
Completed NCT03618472 - Comparison of the Effectiveness Metformin for Deceasing Proliferative Marker in Endometrial Cancer Cells N/A
Recruiting NCT04581447 - Extending Time Without Diabetes After Bariatric Surgery: a Trial Comparing the Metformin Addition or Not to Standard Care Phase 3