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Clinical Trial Summary

This is an open-label, multi-center study to evaluate the safety, tolerability, and anti-tumor activity of SNK01 in combination with AFM24 in subjects with advanced or metastatic EGFR-expressing cancers.


Clinical Trial Description

The study will be conducted in two phases. The Phase 1/dose escalation phase will gather preliminary safety and tolerability data for escalating doses of AFM24 in combination with SNK01 at a fixed dose in order to determine the MTD/RP2D for the combination dose regimen to be used in the Phase 2a/expansion. The Phase 2a/expansion portion of the study will gather additional safety, tolerability, efficacy, and anti-tumor activity information for the combination of AFM24 with SNK01 in subjects with three types of advanced or metastatic EGFR-expressing cancers. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05099549
Study type Interventional
Source NKGen Biotech, Inc.
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date November 3, 2021
Completion date September 21, 2023

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