Metastatic Colorectal Cancer Clinical Trial
Official title:
Irinotecan in Combination With Trifluridine-tipiracil and Bevacizumab in Pre-treated Metastatic Colorectal Cancer
The goal of this multicenter, single-arm, observational cohort study is to investigate the efficacy and safety of irinotecan in combination with trifluridine-tipiracil and bevacizumab in colorectal cancer with prior oxaliplatin and fluoropyrimidine-based chemotherapy (including 5-FU/capecitabine/S-1) exposure in the metastatic setting or within 12 months of recurrence.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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A Trial to Compare Oxaliplatin, Folinic Acid (FA) and 5-Fluorouracil (5FU) Combination Chemotherapy (FOLFOX-4) With or Without Cetuximab in the 1st Line Treatment of Metastatic Colorectal Cancer (mCRC) in Chinese Rat Sarcoma Viral Oncogene Homolog (RAS) Wild-type Patients
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Phase 3 | |
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A Prospective Observational Cohort Study Evaluating Resection Rate in Patients With Metastatic Colorectal Cancer Treated With Aflibercept in Combination With FOLFIRI - Observatoire résection
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| Completed |
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Phase 1/Phase 2 | |
| Withdrawn |
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Phase 2 | |
| Withdrawn |
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FOLFOX + Immunotherapy With Intrahepatic Oxaliplatin for Patients With Metastatic Colorectal Cancer
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Phase 2 | |
| Withdrawn |
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Epacadostat in Combination With Pembrolizumab and Azacitidine in Subjects With Metastatic Colorectal Cancer
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Phase 1/Phase 2 | |
| Recruiting |
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Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer
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Phase 2 | |
| Terminated |
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Phase 1 | |
| Completed |
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| Not yet recruiting |
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Regorafenib in Combination With Multimodal Metronomic Chemotherapy for Chemo-resistant Metastatic Colorectal Cancers
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Phase 2 | |
| Not yet recruiting |
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18FFDG PET/CT for Early Evaluation of Chemotherapy Efficacy in Metastatic Colic Adenocarcinoma
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| Withdrawn |
NCT03982173 -
Basket Trial for Combination Therapy With Durvalumab (Anti-PDL1) (MEDI4736) and Tremelimumab (Anti-CTLA4) in Patients With Metastatic Solid Tumors
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Phase 2 | |
| Completed |
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Study of Irinotecan and AZD1775, a Selective Wee 1 Inhibitor, in RAS or BRAF Mutated, Second-line Metastatic Colorectal Cancer
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Phase 1 | |
| Active, not recruiting |
NCT02575378 -
Maintenance Treatment With Capecitabine Metronomic Chemotherapy and Chinese Traditional Medicine in Metastatic Colorectal Cancer
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Phase 4 | |
| Withdrawn |
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Abscopal Effect for Metastatic Colorectal Cancer
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Phase 2 | |
| Recruiting |
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Chemotherapy-related Toxicity, Nutritional Status and Quality of Life
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N/A | |
| Active, not recruiting |
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Evaluation of MGN1703 Maintenance Treatment in Patients With mCRC With Tumor Reduction During Induction Treatment
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Phase 3 | |
| Completed |
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Study to Compare CAPTEM vs FOLFIRI as Second Line Treatment in Advanced, Colorectal Cancer Patients
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Phase 2 | |
| Active, not recruiting |
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Study to Determine the Efficacy of Regorafenib in Metastatic Colorectal Cancer Patients and to Discover Biomarkers
|
Phase 2 | |
| Withdrawn |
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A Phase II Study of IMMU 130 in Patients With Metastatic Colorectal Cancer
|
Phase 2 |