Metastatic Colorectal Cancer Clinical Trial
Official title:
Phase II Trial of Early-Line Anti-EGFR Therapy to Facilitate Retreatment for Select Patients With Metastatic Colorectal Cancer
The study will use previously established doses of panitumumab or cetuximab in the metastatic setting for the treatment of unresectable colorectal cancer (CRC). It is designed to investigate an alternative treatment strategy to maximize the benefit to inhibition of epidermal growth factor receptor (EGFR) for a highly selected patient population. It will enroll 71 participants with left-sided, unresectable metastatic CRC. Participants will be on study up to 5 years.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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A Trial to Compare Oxaliplatin, Folinic Acid (FA) and 5-Fluorouracil (5FU) Combination Chemotherapy (FOLFOX-4) With or Without Cetuximab in the 1st Line Treatment of Metastatic Colorectal Cancer (mCRC) in Chinese Rat Sarcoma Viral Oncogene Homolog (RAS) Wild-type Patients
|
Phase 3 | |
| Completed |
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A Prospective Observational Cohort Study Evaluating Resection Rate in Patients With Metastatic Colorectal Cancer Treated With Aflibercept in Combination With FOLFIRI - Observatoire résection
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| Completed |
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|
Phase 1/Phase 2 | |
| Withdrawn |
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Niraparib Maintenance Treatment in mCRC With a Partial o Complete Response After Oxaliplatin-based Induction Therapy
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Phase 2 | |
| Withdrawn |
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FOLFOX + Immunotherapy With Intrahepatic Oxaliplatin for Patients With Metastatic Colorectal Cancer
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Phase 2 | |
| Withdrawn |
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Epacadostat in Combination With Pembrolizumab and Azacitidine in Subjects With Metastatic Colorectal Cancer
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Phase 1/Phase 2 | |
| Recruiting |
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Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer
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Phase 2 | |
| Terminated |
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Phase 1 | |
| Completed |
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HepaSphere™ Microspheres Prospective Registry
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| Not yet recruiting |
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Regorafenib in Combination With Multimodal Metronomic Chemotherapy for Chemo-resistant Metastatic Colorectal Cancers
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Phase 2 | |
| Not yet recruiting |
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18FFDG PET/CT for Early Evaluation of Chemotherapy Efficacy in Metastatic Colic Adenocarcinoma
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||
| Withdrawn |
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Basket Trial for Combination Therapy With Durvalumab (Anti-PDL1) (MEDI4736) and Tremelimumab (Anti-CTLA4) in Patients With Metastatic Solid Tumors
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Phase 2 | |
| Completed |
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Phase 1 | |
| Active, not recruiting |
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Maintenance Treatment With Capecitabine Metronomic Chemotherapy and Chinese Traditional Medicine in Metastatic Colorectal Cancer
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Phase 4 | |
| Withdrawn |
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Abscopal Effect for Metastatic Colorectal Cancer
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Phase 2 | |
| Recruiting |
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Chemotherapy-related Toxicity, Nutritional Status and Quality of Life
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N/A | |
| Active, not recruiting |
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Evaluation of MGN1703 Maintenance Treatment in Patients With mCRC With Tumor Reduction During Induction Treatment
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Phase 3 | |
| Completed |
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Study to Compare CAPTEM vs FOLFIRI as Second Line Treatment in Advanced, Colorectal Cancer Patients
|
Phase 2 | |
| Active, not recruiting |
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Study to Determine the Efficacy of Regorafenib in Metastatic Colorectal Cancer Patients and to Discover Biomarkers
|
Phase 2 | |
| Withdrawn |
NCT01915472 -
A Phase II Study of IMMU 130 in Patients With Metastatic Colorectal Cancer
|
Phase 2 |