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Clinical Trial Summary

the efficacy and safety of BBI608 in combination with pembrolizumab


Clinical Trial Description

This is a multicenter, open-label Phase Ib/II study to exploratively evaluate the efficacy and safety of BBI608 in combination with pembrolizumab in patients with metastatic colorectal cancer (CRC) not responded to or intolerant of standard chemotherapy.The same analysis will be performed for the additional cohort to the Phase II part, consisting of patients with metastatic CMS 1 or 4, MMS, CRC not responsive to or intolerant of standard chemotherapy. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02851004
Study type Interventional
Source National Cancer Center Hospital East
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date October 2016
Completion date August 23, 2021

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