Metabolic Health Clinical Trial
Official title:
Acute Effects of Breaking Prolonged Sitting on Postprandial Glycaemic Response, Incretin Hormones Secretion and Eating Behaviour in Sedentary Lean Adults
Verified date | April 2024 |
Source | National Taiwan Normal University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this project is to investigate the effects of breaking up prolonged sitting on postprandial metabolic responses, gut hormones secretion and energy balance in sedentary lean adults.
Status | Completed |
Enrollment | 13 |
Est. completion date | March 1, 2023 |
Est. primary completion date | March 1, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years to 45 Years |
Eligibility | Inclusion Criteria: - Physical inactive males and females - Aged between 20 and 45 years - Lean healthy (waist circumference less than 90 cm for males and 80 cm for females) - Weight stable for more than 3 months (no change in weight +/- 3%) - Non-smoker - Able to walk comfortably on a treadmill Exclusion Criteria: - Personal history of/existing diabetes, cardiovascular disease, metabolic disease or dyslipidaemia - Waist circumference > 90 cm for male and > 80 cm for female - Taking medications that may influence lipid or carbohydrate metabolism or immune system function - Unable to take part in exercise for any reason (e.g., injury or disability) or a positive response to any questions on the Physical Activity Readiness questionnaire (PAR-Q) |
Country | Name | City | State |
---|---|---|---|
Taiwan | National Taiwan Normal University | Taipei |
Lead Sponsor | Collaborator |
---|---|
National Taiwan Normal University |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Gut hormones responses | Changes in blood gut hormones responses (e.g., GLP-1, PYY and GIP concentrations measured in pmol/L) between trials | 320 minutes | |
Secondary | Visual analogue scale (VAS) | Changes in VAS from 0-100 mm (e.g., appetite and mood, etc.) between trials | 320 minutes | |
Secondary | Energy intake | Changes in energy intake (e.g, using a food diary to record) after leaving the laboratory until midnight | 600 minutes after leaving the laboratory | |
Secondary | Physical activity level | Changes in physical activity level (e.g., using an accelerometer to record) after leaving the laboratory until midnight | 600 minutes after leaving the laboratory | |
Secondary | Lipid profile | Changes in blood lipid profile (e.g., TAG and cholesterol, etc.) between trials | 320 minutes | |
Secondary | Blood pressure | Changes in blood pressure (systolic and diastolic blood pressure) between trials | 320 minutes | |
Secondary | Computerized cognitive testing | Changes in cognitive function (e.g., accuracy and reaction time) between trials | 320 minutes | |
Secondary | Incremental area under curve (iAUC) for metabolic health | Changes in incremental area under curve (iAUC) for insulin and glucose between trials | 320 minutes |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05564273 -
Viome Nutritional Programs to Improve Clinical Outcomes for Metabolic Conditions
|
N/A | |
Completed |
NCT04389736 -
Effects of NMES on Energy Expenditure, Glycaemia and Hormonal Responses to Glucose Ingestion
|
N/A | |
Completed |
NCT01767051 -
Children Follow-up of PCOS Women
|
N/A | |
Recruiting |
NCT03670524 -
Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Project
|
N/A | |
Completed |
NCT03082131 -
Resistant Starch Wheat for Improved Metabolic Health
|
N/A | |
Completed |
NCT03842514 -
Food Additives - Do Processed Diets Impact on Gut and Metabolic Health
|
N/A | |
Recruiting |
NCT05308381 -
Breakfast, Exercise and Metabolic Health in Healthy Women
|
N/A | |
Recruiting |
NCT05291065 -
Breakfast, Exercise and Metabolic Health in Healthy Men
|
N/A | |
Completed |
NCT03969745 -
Effects of Two-weeks of Time Restricted Feeding on Basal and Postprandial Metabolism in Healthy Men
|
N/A | |
Recruiting |
NCT05820490 -
ImpaCt Of Shiftwork on METabolic Flexibility and Skeletal Muscle Clocks
|
||
Completed |
NCT02585336 -
Changes in Sugar-sweetened Beverage Intake and Metabolic Health: Improving Metabolic Profile Very Effortlessly
|
N/A | |
Not yet recruiting |
NCT05912699 -
A Study to Evaluate the Effect of SlimBiotics L. Fermentum K8 Postbiotic on Weight Management and Metabolic Health Outcomes
|
N/A | |
Withdrawn |
NCT06354101 -
The Purpose of This Registry Study is to Learn More About Metabolic Health: Approximately 15,000 Participants Who Are Overweight or Have Obesity With or Without Metabolic Diseases Are Expected to Participate in This Registry Study.
|
||
Not yet recruiting |
NCT05917314 -
A Study to Evaluate the Effect of SlimBiotics Probiotic Formula on Weight Management and Metabolic Health Outcomes
|
N/A | |
Recruiting |
NCT05774574 -
Physiological and Appetitive Effects of CBD Supplementation
|
N/A | |
Completed |
NCT05306678 -
Breaking Sitting and Metabolic Health in Sedentary Overweight and Obese Adults
|
N/A | |
Completed |
NCT05911490 -
Effects of Breaking Sitting on Human Behaviour and Metabolic Health
|
N/A |