Metabolic Diseases Clinical Trial
— METARUNOfficial title:
Etude Des Troubles métaboliques Induits Par Une Course à Pied très Longue Distance, " La Diagonale Des Fous " de La Réunion / Metabolic Disorders in Ultramarathon Runners of the Madmen's Diagonal Race on Reunion Island
Acute consequences of ultramarathon running are still unknown as very little research has been done on the matter. The investigators will assess the consequences on the metabolism of runners in the ultramarathon Madmen's Diagonal on Reunion Island. Data from the literature suggest that runners undergo loss of zinc, copper, iron, magnesium not unlike the loss of metabolites in systemic inflammatory response syndrome. The purpose of this study is to assess the metabolic disorders (selenium, zinc, vitamins B9 and B12) in ultramarathon runners, during and up to 28 days after the Madmen's Diagonal which takes place on Reunion Island every year in October.
Status | Completed |
Enrollment | 106 |
Est. completion date | November 2014 |
Est. primary completion date | November 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Ultramarathon runner in the Madmen's Diagonal on Reunion Island (October 2014 ) - Aged 18 years or older - Lives on Reunion Island - Gave informed consent - Medical certificate allowing the participation in an ultramarathon Exclusion Criteria: - Aged less than 18 years Ultramarathon runner in the Bourbon Trail or Mascarenes races (which take place at the same time as the Madmen's Diagonal) |
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
Country | Name | City | State |
---|---|---|---|
France | Reunion Island University Hospital | Saint Denis | Reunion Island |
Lead Sponsor | Collaborator |
---|---|
Centre Hospitalier Universitaire de la Réunion |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Assess the selenium levels | Blood wil be analyzed prior to the start of the race, upon completion of the race (anywhere between 27 and 67 hours after the start of the race), and upon days 7 and 28. Blood will be drawn in the same medical laboratory at the Reunion Island University Hospital site of Saint Denis. | 28 days | No |
Secondary | - Assess Ions and trace metals (Sodium, Potassium, Chloride, Zinc) | 28 days | No | |
Secondary | - Assess Renal function tests (creatinine, blood urea nitrogen) | 28 days | No | |
Secondary | - Assess liver function (total protein, cardiac markers (myoglobin, CPK-MB) | 28 days | No | |
Secondary | - Assess iron and ferritin | 28 days | No | |
Secondary | - Assess blood disorder (vitamin B12, folic acid or vitamin B9) | 28 days | No | |
Secondary | - Assess hematology disorder | 28 days | No | |
Secondary | Fatigue assessment: assessed via a visual analogue scale | Fatigue will be assessed via a visual analogue scale | 28 days | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02402985 -
Comparison of a Plant Protein Diet to a Animal Protein Diet Emphasized in Type 2 Diabetics
|
N/A | |
Completed |
NCT02380846 -
The Metabolic Effects of Consuming Carbohydrate With Different Protein Types
|
N/A | |
Not yet recruiting |
NCT01916603 -
Diet, Physical Activity and Breastfeeding Intervention on Maternal Nutrition, Offspring Growth and Development
|
N/A | |
Completed |
NCT01616082 -
Effect of Caloric Restriction on Fat Oxidation in Obese Men and Women (Magellan II)
|
N/A | |
Completed |
NCT01737164 -
Effect of Age on Glucose and Lipid Metabolism
|
N/A | |
Terminated |
NCT00935766 -
Effect of Fish Oil (Omega-3 Fatty Acids) on Arteries
|
Phase 3 | |
Enrolling by invitation |
NCT00628199 -
Study to Create Potential Cell-Based Therapies to Treat Human Disease and Disability
|
||
Recruiting |
NCT04958109 -
Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test
|
Phase 1 | |
Completed |
NCT01968720 -
Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia
|
Phase 2 | |
Completed |
NCT01708681 -
Lean Seafood Intake and Postprandial Metabolism
|
N/A | |
Completed |
NCT01719913 -
The Effect of Gluten on Gut Microbiome and Metabolic Health.
|
N/A | |
Completed |
NCT01705782 -
The Effects of Amino Acid Supplement During Acute Inflammation.
|
N/A | |
Completed |
NCT01435382 -
A Pharmacokinetic and Pharmacodynamic Study of PF-04950615 (RN316) in Subjects With Hypercholesterolemia
|
Phase 1 | |
Recruiting |
NCT02629926 -
Transitional Growth Hormone (GH) Use in Growth Hormone Deficient (GHD) Cancer Survivors
|
Phase 4 | |
Completed |
NCT00707746 -
Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects
|
Phase 2 | |
Completed |
NCT00550706 -
Drug Utilization Prevalence in a Pediatric Care Medical Center
|
N/A | |
Completed |
NCT03941392 -
Nutritional Study in Spanish Pediatric Population
|
||
Terminated |
NCT02440945 -
Use of the DBS for the Follow-up of Blood Clinical Parameters of Old People
|
N/A | |
Not yet recruiting |
NCT06000605 -
Brain Substrate Switch to Ketones and Lactate
|
N/A | |
Recruiting |
NCT05236374 -
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
|
N/A |