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Clinical Trial Summary

This research is being done to learn if a new type of haploidentical transplantation using TCR alpha beta and CD19 depleted stem cell graft from the donor is safe and effective to treat the patient's underlying condition. This study will use stem cells obtained via peripheral blood or bone marrow from parent or other half-matched family member donor. These will be processed through a special device called CliniMACS, which is considered investigational.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04414046
Study type Interventional
Source Johns Hopkins All Children's Hospital
Contact Jade Hanson, MSN
Phone 7277676468
Email jade.hanson@jhmi.edu
Status Recruiting
Phase Phase 2
Start date July 22, 2020
Completion date June 30, 2025

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