Mesenteric Panniculitis : Review of Consecutive Abdominal MDCT Examinations With a Matched-pair Analysis

Mesenteric Panniculitis Clinical Trial

— MP - Cancer  

Official title:

Mesenteric Panniculitis : Review of Consecutive Abdominal MDCT Examinations With a Matched-pair Analysis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03316001
• Other study ID #: 2016Ao002
• Status: Completed
• Phase: N/A
• First received: October 17, 2017
• Last updated: October 19, 2017
• Start date: November 2014
• Est. completion date: July 2015

Study information

• Verified date: October 2017
• Source: CHU de Reims
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Mesenteric panniculitis is a benign inflammatory condition that involves the adipose tissue of the intestinal mesentery. Clinical manifestations are uncommon, non specific and atypical. Mesenteric panniculitis is thus most often an incidental finding during an investigation for other reason, mostly on computed tomography scans. The rate of malignancy in patients with mesenteric panniculitis, especially urogenital and gastrointestinal adenocarcinomas or lymphomas, has been reported to be as high, thus suggesting that there may be a relationship between mesenteric panniculitis and progression of an underlying malignancy or the risk of a future malignancy.

Description:

The aim was:

to estimate the prevalence of mesenteric panniculitis. to study relationship between mesenteric panniculitis and malignancy. to investigate the 5-year outcome of patients with mesenteric panniculitis for the development of malignancy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 288
• Est. completion date: July 2015
• Est. primary completion date: March 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

inclusion criteria:

• Patients with a CT scan from January to August 2008

• Patients with diagnosis of mesenteric panniculitis on CT scan

exclusion criteria:

• Patients with disease that may cause mesenteric infiltration

Related Conditions & MeSH terms

• Mesenteric Panniculitis
• Panniculitis

Intervention

Other:
• Review of multidetector row computed tomography scans
multidetector row computed tomography scans

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
CHU de Reims

References & Publications (1)

Protin-Catteau L, Thiéfin G, Barbe C, Jolly D, Soyer P, Hoeffel C. Mesenteric panniculitis: review of consecutive abdominal MDCT examinations with a matched-pair analysis. Acta Radiol. 2016 Dec;57(12):1438-1444. doi: 10.1177/0284185116629829. Epub 2016 Jul 19. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	mesenteric panniculitis	mesenteric panniculitis is identified on the basis on the presence of three of the following 5 signs on CT scan: higher attenuation of the fat of the root of the small bowel mesentery,; a pseudo mass smoothly displacing neighboring structures with a hyperdense pseudocapsule surrounding the mesenteric fat,; lymph nodes within the fatty pseudo mass and; a hypodense halo around the nodes and the blood vessels	Day 0