The Study on the Relationship Among Meridian, Acupoint and Internal Visceral Organs

Meridian Clinical Trial

Official title:

The Study on the Relationship Among Meridian, Acupoint and Internal Visceral Organs

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04172298
• Other study ID #: CMUH106-REC1-089
• Status: Completed
• Phase: N/A
• Start date: August 1, 2017
• Est. completion date: November 1, 2019

Study information

• Verified date: November 2019
• Source: China Medical University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study on the relationship among meridian, acupoint and internal

Description:

Meridian system is the pathway of transporting qi and blood, and that distributes all the body. Meridian system connects to internal visceral organs interior, and also connects to joints (or acupoint) exterior. The relationship among meridian, acupoints and internal visceral organs is still unclear. Therefore, the purpose of the present study was to investigate the relationship among meridian, acupoints and internal visceral organs. Total 33 subjects randomly finished three sessional studies as follows: 1) sham electroacupuncture (EA) session: the stainless steels acupuncture needles inserted into the subcutaneous layer of Zusanli (cathode) and Shangjuxu acupints (anion) , and the needles connected to EA stimulator, but no electric discharge for 30 min; 2) Zusanli session: the acupuncture needles inserted into Zusanli (cathode) and Shangjuxu acupoints (anion), and twisting obtain qi, and the needles then connected to EA stimulator, the frequency was 2 Hz, the duration was 30 min, and the intensity was visual slightly muscle contraction; 3) Shaohai session: the methods were identical Zusanli group, but Shaohai acupoint (cathode), and 3 cm below Shaohai (anion) . The major outcome measure was the changes of the percentage of gastric slow wave and dysrhythmia in 30 min electrogastrogram recordings, and the changes of cardiac output and stroke volume in 30 min recordings. Secondary outcome measure was the changes of saliva, blood and urine metabolites.

The investigators predict the results of the present study can test and verify meridian theory of traditional Chinese Medicine, meridian system connects internal visceral organ interior, and connects joint (or acupoint) exterior.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 33
• Est. completion date: November 1, 2019
• Est. primary completion date: November 1, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 50 Years

Eligibility

Inclusion Criteria:

1. Gender:male or female.

2. Age:from 20 years old (inclusive) to 50 years old (inclusive).

3. After detailed description of the entire research purpose or process, voluntarily participate in the study and sign the consent form.

Exclusion Criteria:

1. Cancer, congestive hear failured NYHA class>II, COPD attack.

2. History of esophagus and gastroduodenal surgery?Barrett's esophagus.

3. Can not accept acupuncture points stimulators.

4. Allergic to acupuncture needles.

5. Has a mental illness or is unable to cooperate with the researcher.

Related Conditions & MeSH terms

• Meridian

Intervention

Other:
• sham electroacupuncture (EA) session
The stainless steels acupuncture needles inserted into the subcutaneous layer of Zusanli (cathode) and Shangjuxu acupints (anion) , and the needles connected to EA stimulator, but no electric discharge for 30 min.
• Zusanli session
The acupuncture needles inserted into Zusanli (cathode) and Shangjuxu acupoints (anion), and twisting obtain qi, and the needles then connected to EA stimulator, the frequency was 2 Hz, the duration was 30 min, and the intensity was visual slightly muscle contraction.
• Shaohai session
The methods were identical Zusanli group, but Shaohai acupoint (cathode), and 3 cm below Shaohai (anion).

Locations

Country	Name	City	State
Taiwan	China Medical University Hospital	Taichung	North District

Sponsors (1)

Lead Sponsor	Collaborator
China Medical University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	electrogastrogram recordings	the changes of the percentage of gastric slow wave .	30 minutes in duration.
Primary	cardiac output	the changes of cardiac output .	30 minutes in duration.
Primary	cardiac output	the changes of stroke volume .	30 minutes in duration.