Effects of Estrogen and Hot Flashes on Mood in Postmenopausal Women

Menopausal Depression Clinical Trial

Official title:
Effects of Estrogen and Hot Flashes on Mood in Postmenopausal Women

Status Terminated

Clinical Trial Summary

This protocol is a controlled study of estradiol therapy in early postmenopausal women with and without frequent hot flashes that will be used to determine whether hot flashes are an important intermediary in the generation of menopause-associated depression.

Clinical Trial Description

SPECIFIC AIMS (Research Objectives)

To define the relative effects of hot flashes and changes in estradiol on mood in postmenopausal women:

Hypotheses:

1. Estrogen treatment has a similar therapeutic effect on mood in women with and without frequent hot flashes

2. Estradiol levels correlate with improvement in mood ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01126801
Study type	Interventional
Source	Massachusetts General Hospital
Contact
Status	Terminated
Phase	Phase 2
Start date	May 2010
Completion date	February 2011

View Details

See also
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Completed	`NCT02480192` - Cognitive Behavioural Therapy for Menopausal Symptoms	N/A
Completed	`NCT01470092` - Tibolone and Placebo in Adjunct to Antidepressant Medication for Women With Menopausal Depression	Phase 4