Meniscus Disorder Clinical Trial
Official title:
Carotid Flow Time Measurement Guided Fluid Management During Spinal Anesthesia
Fluid management is a fundamental aspect of anesthesia. Several monitorization methods have been introduced to optimize fuid management. To date neither of them were ideal. Corrected flow time measurement (FTc) in the carotid artery was recently introduced to detect fluid responsiveness. Spinal anesthesia causes hypotension and fluid preloading is suggested to overcome this problem. The aim of this study is to evaluate the effect of FTc guided fluid loading on spinal anesthesia induced hypotension.
Status | Not yet recruiting |
Enrollment | 20 |
Est. completion date | December 2022 |
Est. primary completion date | September 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 19 Years to 80 Years |
Eligibility | Inclusion Criteria: - Adult patients (19-80 years of age) who were scheduled to undergo arthroscopic knee surgery under spinal anesthesia Exclusion Criteria: - Mean blood pressure < 70 mmHg before induction of general anesthesia - Patients who have currently taken angiotensin-converting enzyme inhibitor - Patients who have currently taken angiotensin receptor blocker - the presence of carotid artery stenosis > 50% - cardiac rhythm other than sinus - unstable angina - a left ventricular ejection fraction of < 40% - severe vascular disease - implanted pacemaker/cardioverter - autonomic nervous system disorders - pregnancy |
Country | Name | City | State |
---|---|---|---|
Turkey | Diskapi Yildirim Beyazit Teaching and Research Hospital | Ankara |
Lead Sponsor | Collaborator |
---|---|
Diskapi Teaching and Research Hospital |
Turkey,
Ceruti S, Anselmi L, Minotti B, Franceschini D, Aguirre J, Borgeat A, Saporito A. Prevention of arterial hypotension after spinal anaesthesia using vena cava ultrasound to guide fluid management. Br J Anaesth. 2018 Jan;120(1):101-108. doi: 10.1016/j.bja.2 — View Citation
Lee JE, George RB, Habib AS. Spinal-induced hypotension: Incidence, mechanisms, prophylaxis, and management: Summarizing 20 years of research. Best Pract Res Clin Anaesthesiol. 2017 Mar;31(1):57-68. doi: 10.1016/j.bpa.2017.01.001. Epub 2017 Jan 8. Review. — View Citation
Song Y, Kwak YL, Song JW, Kim YJ, Shim JK. Respirophasic carotid artery peak velocity variation as a predictor of fluid responsiveness in mechanically ventilated patients with coronary artery disease. Br J Anaesth. 2014 Jul;113(1):61-6. doi: 10.1093/bja/a — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of patients with Hypotension | Mean arterial pressure >30% lower than baseline value | 5 minutes after induction of spinal anesthesia | |
Secondary | Number of patients receiving Vasopressor therapy | Ephedrine will be administered if mean arterial pressure drops >30% than baseline value | 5 minutes after induction of spinal anesthesia |
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